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Chronotype

Anatomy and Physiology · NLM MeSH · updated 2026-10-31 · version 1

Citations verified against PubMedNot yet clinician-reviewed10 referencesApproximately 4 min read

The natural inclination or preference of time of day in which an individual or an organism has the most activity, particularly as it relates to sleeping pattern and circadian sleep-wake preferences.

Table of Contents

1. Definition2. Research landscape3. Reading the evidence4. Open-access studies5. Key reviews6. References7. About this article

Definition and research guide

This page combines a MeSH definition, publication statistics and selected research abstracts. It is a starting point for reading the literature, not a medical textbook or a systematic evidence review.

Content available: 4 complete abstracts (851 words), 10 references. Full article text is not stored or reproduced here; follow the PMID, DOI or PMC links to read the original sources and their access terms.

Definition

The natural inclination or preference of time of day in which an individual or an organism has the most activity, particularly as it relates to sleeping pattern and circadian sleep-wake preferences.

Definition: NLM Medical Subject Headings (MeSH) scope note (Public domain (U.S. National Library of Medicine); attribution requested). View the MeSH record.

Also known as: Chronotypes; Morningness Eveningness Preferences; Morningness Eveningness Preference; Preference, Morningness Eveningness.

Where it fits in the MeSH classification

Broader topics
Personality; Circadian Rhythm

Research landscape

PubMed indexes 670 records tagged with the MeSH heading “Chronotype” (counts retrieved 2026-10-31). 670 of them (100.0%) were published from 2020 onward, and the busiest period so far is 2020 onward with 670 records.

Reviews account for 54 records (8.1%) and meta-analyses for 20. Randomized controlled trials number 18 (2.7%) as a share of all records on the topic.

PubMed records by publication periodthrough 1999: 0 records; 2000-2009: 0 records; 2010-2019: 0 records; 2020 onward: 670 records0through 199902000-200902010-20196702020 onward
Records in PubMed indexed with this heading, by publication period. Real counts from NCBI E-utilities; the final period covers only part of the current year. Volume reflects how much has been published, not how strong the evidence is.
Show the data
PeriodRecords
through 19990
2000-20090
2010-20190
2020 onward670
Share of records by publication typeReviews: 8.1 percent; Meta-analyses: 3.0 percent; Randomized controlled trials: 2.7 percentReviews8.1% (54)Meta-analyses3.0% (20)Randomized controlled trials2.7% (18)
Share of all PubMed records on this heading that carry each publication type. Types overlap with other records, so the shares do not sum to 100%.
Publication-type chart data
Publication types among 670 PubMed records
TypeRecordsShare
Reviews548.1%
Meta-analyses203.0%
Randomized controlled trials182.7%

Method: PubMed query "Chronotype"[MeSH Terms] with publication-type and date filters, retrieved 2026-10-31.

Reading the evidence in anatomy and physiology

Anatomy describes how body structures are built and physiology describes how they normally work, so most findings here are descriptive or mechanistic rather than evidence about treatment. Much of what is known comes from dissection, imaging, tissue studies and experiments in animals, and measurements in healthy volunteers can differ from those in people with disease or at different ages. Normal ranges vary between individuals and populations. Check whether a result was measured in people or in another species, the age and health of the participants, and the method used.

Evidence from open-access studies

These open-access studies come from PubMed’s best-match results for this heading (papers whose main topic it is), ranked here by citation count, with one recent addition. Each abstract is reproduced in full under its recorded open licence so that you can read the authors’ own words. They illustrate the literature; they are not a systematic summary of it. Citation counts measure attention, not reliability or clinical benefit.

Study comparison — selected abstracts, not a systematic review
Study / authorsYearSource label / designEurope PMC citationsLicence / source
Chronotype is associated with eating behaviors, physical activity and overweight in school-aged children
Yang Y, Li SX, Zhang Y, Wang F, Jiang DJ, Wang SJ, et al.
2023Research article
Design not recorded in structured metadata
29cc by
PMID 37798740 · DOI · PMC10557201
Chronotype and Sleep Quality in Obesity: How Do They Change After Menopause?
Verde L, Barrea L, Vetrani C, Frias-Toral E, Chapela SP, Jayawardena R, et al.
2022Review article
Design not recorded in structured metadata
28cc by
PMID 36053414 · DOI · PMC9729134
The association between metabolic parameters and evening chronotype and social jetlag in non-shift workers: A meta-analysis
Zhang R, Cai X, Lin C, Yang W, Lv F, Wu J, et al.
2022Meta-analysis
Design not recorded in structured metadata
27cc by
PMID 36479212 · DOI · PMC9720311
A Novel Chronotype-Based Mediterranean Diet Pyramid: An Updated Representation by the Italian Society of Endocrinology (SIE) and the Italian Society of Dietetics and Clinical Nutrition (ADI)
Barrea L, Verde L, Camajani E, Annunziata G, Mollica MP, Minnetti M, et al.
2026Review article
Design not recorded in structured metadata
2cc by
PMID 41686324 · DOI · PMC12904983

Chronotype is associated with eating behaviors, physical activity and overweight in school-aged children [1]

Research article Yang Y, Li SX, Zhang Y, Wang F, Jiang DJ, Wang SJ, et al. · · 2023 · cited 29 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
BackgroundA later chronotype has been found to be associated with unhealthy habits and diseases, such as an unhealthy diet and metabolic syndrome in adults.
Closing excerpt
The findings showed that children with early chronotype is associated with more active, healthier dietary behaviors, longer sleep duration, short social jet lag, and a lower risk of overweight.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (271 words)

BackgroundA later chronotype has been found to be associated with unhealthy habits and diseases, such as an unhealthy diet and metabolic syndrome in adults. Little is known about the association between chronotype, eating habits, physical activity and obesity. Thus, this study aimed to explore the relationships between chronotype, eating behaviors, physical activity, and overweight in Chinese school-aged children.MethodsData from this study was based on 952 schoolchildren (10-12 y) from six primary schools that participated in China. Anthropometric measurements of height and body weight were performed. Information about sleeping habits, dietary behaviors, and other lifestyle behaviors was gathered using a self-administered questionnaire. Multiple linear regression analysis or multivariable logistic regression model was performed to assess the associations between chronotype, eating behaviors, physical activity, and overweight.ResultsNearly 70% (69.9%) of the participants had a self-reported morning chronotype. Multiple linear regression analysis revealed chronotype score was positively associated with physical activities (all P values ConclusionsThis study indicates that early chronotype children are more active, have healthier dietary habits, get more sleep, have shorter social jet lag, and are less likely to be overweight than non-early chronotype children. Our findings suggest that later chronotype may be a potential indicator in the early detection of overweight, unhealthy eating, and physical inactivity behaviors. Chronotype has been found to have an important impact on individual's health. In the present study, we conducted a cross-sectional study to investigate the association between chronotype, eating behaviors, physical activity, and overweight in school-aged children. The findings showed that children with early chronotype is associated with more active, healthier dietary behaviors, longer sleep duration, short social jet lag, and a lower risk of overweight.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 37798740 · DOI · PMC10557201

Chronotype and Sleep Quality in Obesity: How Do They Change After Menopause? [2]

Review article Verde L, Barrea L, Vetrani C, Frias-Toral E, Chapela SP, Jayawardena R, et al. · · 2022 · cited 28 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
Purpose of reviewThis review primarily provides an overview of the current evidence on chronotype (which reflects an individual's preference for the timing of sleeping, eating, and activity in a 24-h period) and sleep quality changes in obesity in postmenopausal women.
Closing excerpt
In the management of postmenopausal women, especially those experiencing obesity, careful assessment of sleep disturbances and chronotype and subsequent development of the most appropriate treatment, including nutritional management, should be part of the treatment routine.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (160 words)

Purpose of reviewThis review primarily provides an overview of the current evidence on chronotype (which reflects an individual's preference for the timing of sleeping, eating, and activity in a 24-h period) and sleep quality changes in obesity in postmenopausal women. It also explores possible nutritional strategies to manage these changes in this phase of a woman's life.Recent findingsMenopause is a life stage frequently associated with sleep disturbances and changes in circadian rhythms. Sleep disturbances are one of the main symptoms of menopause and are caused by several factors such as hormonal changes, obesity, and melatonin reduction. In addition, the chronotype also changes following menopause. Nutritional strategies are essential because they could help manage menopausal sleep disturbances and circadian misalignment, particularly by tackling obesity and overweight. In the management of postmenopausal women, especially those experiencing obesity, careful assessment of sleep disturbances and chronotype and subsequent development of the most appropriate treatment, including nutritional management, should be part of the treatment routine.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 36053414 · DOI · PMC9729134

The association between metabolic parameters and evening chronotype and social jetlag in non-shift workers: A meta-analysis [3]

Meta-analysis Zhang R, Cai X, Lin C, Yang W, Lv F, Wu J, et al. · · 2022 · cited 27 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
AimsThe aim of the study was to evaluate the association between evening chronotype and social jetlag (SJL) with obesity, blood glucose and lipid levels in non-shift working adults.
Closing excerpt
uk/PROSPERO/, identifier CRD42022303401.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (128 words)

AimsThe aim of the study was to evaluate the association between evening chronotype and social jetlag (SJL) with obesity, blood glucose and lipid levels in non-shift working adults.MethodsThe databases of MEDLINE, EMBASE and Cochrane Reviews were searched for studies analyzing the metabolic parameters among groups of different chronotypes or SJL until Feb 2022. Weighted mean difference (WMD) and 95% confidence intervals (CI) were used to analyze the association between these parameters and chronotypes or SJL.ResultsA total of 27 studies were included in this meta-analysis. Compared with morning chronotype, the participants with evening chronotype had higher body mass index (BMI) (WMD= 0.44 kg/m2, 95%CI, 0.30 to 0.57 kg/m2, pConclusionsEvening chronotype and SJL were associated with obesity and unfavorable metabolic parameters of glucose and lipid metabolism.Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier CRD42022303401.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 36479212 · DOI · PMC9720311

A Novel Chronotype-Based Mediterranean Diet Pyramid: An Updated Representation by the Italian Society of Endocrinology (SIE) and the Italian Society of Dietetics and Clinical Nutrition (ADI) [4]

Review article Barrea L, Verde L, Camajani E, Annunziata G, Mollica MP, Minnetti M, et al. · · 2026 · cited 2 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
PURPOSE OF REVIEW: This review explores the integration of chronobiology and chronotype-specific factors into the Mediterranean Diet (MD) framework.
Closing excerpt
A chronotype-oriented MD pyramid may enhance adherence, optimize metabolic flexibility, and reinforce the MD as a holistic model encompassing nutrition, lifestyle, and sustainability.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (292 words)

PURPOSE OF REVIEW: This review explores the integration of chronobiology and chronotype-specific factors into the Mediterranean Diet (MD) framework. While the MD is widely recognized for its cardiometabolic and neuroprotective effects, current guidelines do not address the timing of food intake or the influence of individual chronotype. Given the growing evidence linking circadian alignment, meal timing, and metabolic health, we propose a revised Mediterranean Diet pyramid tailored to chronotype and lifestyle determinants, herein referred to as the chronotype-based Mediterranean Diet Pyramid of the Italian Society of Endocrinology (SIE) and the Italian Society of Dietetics and Clinical Nutrition (ADI). RECENT FINDINGS: Chrononutrition emphasizes the timing, frequency, and regularity of meals as key elements for metabolic regulation. Early-day energy intake, time-restricted eating, and alignment with circadian rhythms improve glycemic control, weight management, and cardiovascular outcomes. Morning chronotypes tend to show higher adherence to the MD, whereas evening chronotypes more frequently delay meals, skip breakfast, and consume energy-dense foods at night, contributing to poorer metabolic profiles. Sleep duration and quality further modulate appetite regulation and dietary adherence. Building on these insights, the proposed pyramid integrates circadian cues, represented by sun and moon symbols, to guide nutrient timing. Foods rich in carbohydrates and fiber (whole grains, legumes, fruits) are emphasized earlier in the day, while protein- and vegetable-based meals are prioritized in the evening, alongside sleep-promoting foods such as dairy, nuts, and seeds. Lifestyle pillars, including physical activity, adequate sleep, and the alignment of eating schedules with chronotype, form the foundation of the pyramid. The integration of chronobiological principles into the MD offers a novel paradigm that couples dietary quality with circadian alignment. A chronotype-oriented MD pyramid may enhance adherence, optimize metabolic flexibility, and reinforce the MD as a holistic model encompassing nutrition, lifestyle, and sustainability.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 41686324 · DOI · PMC12904983

Key reviews and meta-analyses

The most cited review-type papers among PubMed’s best-match results for this heading, listed with bibliographic details only. Follow the links for the full text and access terms.

  • Research article Chronotype Differences in Body Composition, Dietary Intake and Eating Behavior Outcomes: A Scoping Systematic Review [5]
    van der Merwe C, Münch M, Kruger R · Adv Nutr · 2022 · cited 118 times (Europe PMC)
  • Research article Role of chronotype in dietary intake, meal timing, and obesity: a systematic review [6]
    Teixeira GP, Guimarães KC, Soares AGNS, Marqueze EC, Moreno CRC, Mota MC, et al. · Nutr Rev · 2022 · cited 110 times (Europe PMC)
  • Research article Beyond sleep: A multidimensional model of chronotype [7]
    Chauhan S, Norbury R, Faßbender KC, Ettinger U, Kumari V · Neurosci Biobehav Rev · 2023 · cited 46 times (Europe PMC)
  • Research article The relationship between chronotype and obesity: A systematic review [8]
    Ekiz Erim S, Sert H · Chronobiol Int · 2023 · cited 41 times (Europe PMC)
  • Research article Factors associated with chronotype, job burnout, and perceived stress among nurses in Chinese tertiary hospitals: A multicenter cross-sectional study [9]
    Li L, Wang X, Zhou J, Liu M, Wang S, Zhou Y, et al. · Chronobiol Int · 2024 · cited 17 times (Europe PMC)
  • Research article Association between matched chronotype and poor mental health among shift workers: a systematic review and meta-analysis [10]
    Li B, Liao G, Lee PMY, Huss A, Ma YTJ, Chan JW, et al. · J Epidemiol Community Health · 2023 · cited 13 times (Europe PMC)

References

  1. Yang Y, Li SX, Zhang Y, Wang F, Jiang DJ, Wang SJ, et al.. Chronotype is associated with eating behaviors, physical activity and overweight in school-aged children. . 2023. PMID 37798740 · DOI · PMC10557201
  2. Verde L, Barrea L, Vetrani C, Frias-Toral E, Chapela SP, Jayawardena R, et al.. Chronotype and Sleep Quality in Obesity: How Do They Change After Menopause?. . 2022. PMID 36053414 · DOI · PMC9729134
  3. Zhang R, Cai X, Lin C, Yang W, Lv F, Wu J, et al.. The association between metabolic parameters and evening chronotype and social jetlag in non-shift workers: A meta-analysis. . 2022. PMID 36479212 · DOI · PMC9720311
  4. Barrea L, Verde L, Camajani E, Annunziata G, Mollica MP, Minnetti M, et al.. A Novel Chronotype-Based Mediterranean Diet Pyramid: An Updated Representation by the Italian Society of Endocrinology (SIE) and the Italian Society of Dietetics and Clinical Nutrition (ADI). . 2026. PMID 41686324 · DOI · PMC12904983
  5. van der Merwe C, Münch M, Kruger R. Chronotype Differences in Body Composition, Dietary Intake and Eating Behavior Outcomes: A Scoping Systematic Review. Adv Nutr. 2022. PMID 36041181 · DOI · PMC9776742
  6. Teixeira GP, Guimarães KC, Soares AGNS, Marqueze EC, Moreno CRC, Mota MC, et al.. Role of chronotype in dietary intake, meal timing, and obesity: a systematic review. Nutr Rev. 2022. PMID 35771674 · DOI
  7. Chauhan S, Norbury R, Faßbender KC, Ettinger U, Kumari V. Beyond sleep: A multidimensional model of chronotype. Neurosci Biobehav Rev. 2023. PMID 36868368 · DOI
  8. Ekiz Erim S, Sert H. The relationship between chronotype and obesity: A systematic review. Chronobiol Int. 2023. PMID 36803075 · DOI
  9. Li L, Wang X, Zhou J, Liu M, Wang S, Zhou Y, et al.. Factors associated with chronotype, job burnout, and perceived stress among nurses in Chinese tertiary hospitals: A multicenter cross-sectional study. Chronobiol Int. 2024. PMID 38953516 · DOI
  10. Li B, Liao G, Lee PMY, Huss A, Ma YTJ, Chan JW, et al.. Association between matched chronotype and poor mental health among shift workers: a systematic review and meta-analysis. J Epidemiol Community Health. 2023. PMID 37258217 · DOI

About this article

Sources
NLM Medical Subject Headings (definition, synonyms); NCBI PubMed (counts, identifiers); Europe PMC (open-access abstracts and citation counts).
Verification
Every reference was resolved against PubMed on 2026-10-31; title, year and DOI matched.
Review state
automated source verified; no human expert review has been recorded yet.
Version
1, last updated 2026-10-31.

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At a glance

670
PubMed records on this heading
100%
published since 2020
54
review articles
18
randomized trials
10
verified references below

Counts come from PubMed on 2026-10-31; they show how much has been written, not how strong the evidence is.

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