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Wrist Joint

Anatomy and Physiology · NLM MeSH · updated 2026-10-31 · version 1

Citations verified against PubMedNot yet clinician-reviewed10 referencesApproximately 5 min read

The joint that is formed by the distal end of the radius, the articular disc of the distal radioulnar joint, and the proximal row of carpal bones; (scaphoid bone; lunate bone; triquetral bone).

Table of Contents

1. Definition2. Research landscape3. Reading the evidence4. Open-access studies5. Key reviews6. References7. About this article

Definition and research guide

This page combines a MeSH definition, publication statistics and selected research abstracts. It is a starting point for reading the literature, not a medical textbook or a systematic evidence review.

Content available: 4 complete abstracts (940 words), 10 references. Full article text is not stored or reproduced here; follow the PMID, DOI or PMC links to read the original sources and their access terms.

Definition

The joint that is formed by the distal end of the radius, the articular disc of the distal radioulnar joint, and the proximal row of carpal bones; (scaphoid bone; lunate bone; triquetral bone).

Definition: NLM Medical Subject Headings (MeSH) scope note (Public domain (U.S. National Library of Medicine); attribution requested). View the MeSH record.

Also known as: Joints, Wrist; Joint, Wrist; Wrist Joints.

Where it fits in the MeSH classification

Broader topics
Hand Joints
Narrower topics
Triangular Fibrocartilage

Related concepts

  • Radius
  • Carpal Bones
  • Scaphoid Bone
  • Lunate Bone

Research landscape

PubMed indexes 12,675 records tagged with the MeSH heading “Wrist Joint” (counts retrieved 2026-10-31). 2,502 of them (19.7%) were published from 2020 onward, and the busiest period so far is through 1999 with 4,358 records.

Reviews account for 1,400 records (11.0%) and meta-analyses for 60. Randomized controlled trials number 269 (2.1%) as a share of all records on the topic.

PubMed records by publication periodthrough 1999: 4,358 records; 2000-2009: 2,287 records; 2010-2019: 3,528 records; 2020 onward: 2,502 records4,358through 19992,2872000-20093,5282010-20192,5022020 onward
Records in PubMed indexed with this heading, by publication period. Real counts from NCBI E-utilities; the final period covers only part of the current year. Volume reflects how much has been published, not how strong the evidence is.
Show the data
PeriodRecords
through 19994,358
2000-20092,287
2010-20193,528
2020 onward2,502
Share of records by publication typeReviews: 11.0 percent; Meta-analyses: 0.5 percent; Randomized controlled trials: 2.1 percentReviews11.0% (1,400)Meta-analyses0.5% (60)Randomized controlled trials2.1% (269)
Share of all PubMed records on this heading that carry each publication type. Types overlap with other records, so the shares do not sum to 100%.
Publication-type chart data
Publication types among 12,675 PubMed records
TypeRecordsShare
Reviews1,40011.0%
Meta-analyses600.5%
Randomized controlled trials2692.1%

Method: PubMed query "Wrist Joint"[MeSH Terms] with publication-type and date filters, retrieved 2026-10-31.

Reading the evidence in anatomy and physiology

Anatomy describes how body structures are built and physiology describes how they normally work, so most findings here are descriptive or mechanistic rather than evidence about treatment. Much of what is known comes from dissection, imaging, tissue studies and experiments in animals, and measurements in healthy volunteers can differ from those in people with disease or at different ages. Normal ranges vary between individuals and populations. Check whether a result was measured in people or in another species, the age and health of the participants, and the method used.

Evidence from open-access studies

These open-access studies come from PubMed’s best-match results for this heading (papers whose main topic it is), ranked here by citation count, with one recent addition. Each abstract is reproduced in full under its recorded open licence so that you can read the authors’ own words. They illustrate the literature; they are not a systematic summary of it. Citation counts measure attention, not reliability or clinical benefit.

Study comparison — selected abstracts, not a systematic review
Study / authorsYearSource label / designEurope PMC citationsLicence / source
Gout of hand and wrist: the value of US as compared with DECT
Klauser AS, Halpern EJ, Strobl S, Abd Ellah MMH, Gruber J, Bellmann-Weiler R, et al.
2018Research article
Design not recorded in structured metadata
40cc by
PMID 29679210 · DOI · PMC6132720
Artificial intelligence to diagnosis distal radius fracture using biplane plain X-rays
Oka K, Shiode R, Yoshii Y, Tanaka H, Iwahashi T, Murase T
2021Research article
Design not recorded in structured metadata
38cc by
PMID 34823550 · DOI · PMC8620959
Biomechanical considerations on a CT-based treatment-oriented classification in radius fractures
Hintringer W, Rosenauer R, Pezzei C, Quadlbauer S, Jurkowitsch J, Keuchel T, et al.
2020Review article
Design not recorded in structured metadata
38cc by
PMID 32193681 · DOI · PMC7181558
Mapping wrist motion: 3D CT analysis after scapholunate ligament transection
Promny D, Gill D, Lyer S, Alexiou C, Buder T, Neuhuber W, et al.
2025Research article
Design not recorded in structured metadata
6cc by
PMID 39092658 · DOI · PMC11996708

Gout of hand and wrist: the value of US as compared with DECT [1]

Research article Klauser AS, Halpern EJ, Strobl S, Abd Ellah MMH, Gruber J, Bellmann-Weiler R, et al. · · 2018 · cited 40 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
ObjectivesThe purpose of this study was to compare findings of ultrasound (US) with dual-energy CT (DECT) in patients presenting with suspected gouty hand and wrist arthritis.
Closing excerpt
• Although the sensitivity of US for diagnosis of gouty hand and wrist arthritis is limited, it can be used as a first-line imaging modality in the presence of the DCS.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (217 words)

ObjectivesThe purpose of this study was to compare findings of ultrasound (US) with dual-energy CT (DECT) in patients presenting with suspected gouty hand and wrist arthritis.MethodsThis prospective study included 180 patients (136 men and 44 women, age range, 31- 94 years; mean age, 65.9 years) with an initial clinical diagnosis of acute gouty arthritis who underwent DECT and US examination. Intra- and extra-articular findings of each modality were tabulated and calculated with DECT as gold standard.ResultsThe final diagnosis of gout was positive in 97/180 patients (53.9%) by DECT, an alternative diagnosis confirmed in 83 patients. US showed a sensitivity of 70.1% (extra-articular: 42.5%, p ConclusionsSensitivity of US for diagnosis of gouty arthritis in hand and wrist is limited, particularly with respect to extra-articular urate deposition. The DCS is the most sensitive sign for the assessment of gouty hand and wrist arthritis by US.Key points• Sensitivity of US for diagnosis of gouty arthritis in hand and wrist is limited, particularly with respect to extra-articular gouty deposits. • The double contour sign is the most sensitive finding for the assessment of gouty hand and wrist arthritis by US. • Although the sensitivity of US for diagnosis of gouty hand and wrist arthritis is limited, it can be used as a first-line imaging modality in the presence of the DCS.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 29679210 · DOI · PMC6132720

Artificial intelligence to diagnosis distal radius fracture using biplane plain X-rays [2]

Research article Oka K, Shiode R, Yoshii Y, Tanaka H, Iwahashi T, Murase T · · 2021 · cited 38 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
BackgroundAlthough the automatic diagnosis of fractures using artificial intelligence (AI) has recently been reported to be more accurate than those by orthopedics specialists, big data with at least 1000 images or more are required for deep learning of the convolutional neural network (CNN) to improve diagnostic accuracy.
Closing excerpt
ConclusionsOur method resulted in a good diagnostic rate, even when using a relatively small amount of data.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (311 words)

BackgroundAlthough the automatic diagnosis of fractures using artificial intelligence (AI) has recently been reported to be more accurate than those by orthopedics specialists, big data with at least 1000 images or more are required for deep learning of the convolutional neural network (CNN) to improve diagnostic accuracy. The aim of this study was to develop an AI system capable of diagnosing distal radius fractures with high accuracy even when learning with relatively small data by learning to use bi-planar X-rays images.MethodsVGG16, a learned image recognition model, was used as the CNN. It was modified into a network with two output layers to identify the fractures in plain X-ray images. We augmented 369 plain X-ray anteroposterior images and 360 lateral images of distal radius fractures, as well as 129 anteroposterior images and 125 lateral images of normal wrists to conduct training and diagnostic tests. Similarly, diagnostic tests for fractures of the styloid process of the ulna were conducted using 189 plain X-ray anteroposterior images of fractures and 302 images of the normal styloid process. The distal radius fracture is determined by entering an anteroposterior image of the wrist for testing into the trained AI. If it identifies a fracture, it is diagnosed as the same. However, if the anteroposterior image is determined as normal, the lateral image of the same patient is entered. If a fracture is identified, the final diagnosis is fracture; if the lateral image is identified as normal, the final diagnosis is normal.ResultsThe diagnostic accuracy of distal radius fractures and fractures of the styloid process of the ulna were 98.0 ± 1.6% and 91.1 ± 2.5%, respectively. The areas under the receiver operating characteristic curve were 0.991 {n = 540; 95% confidence interval (CI), 0.984-0.999} and 0.956 (n = 450; 95% CI 0.938-0.973).ConclusionsOur method resulted in a good diagnostic rate, even when using a relatively small amount of data.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 34823550 · DOI · PMC8620959

Biomechanical considerations on a CT-based treatment-oriented classification in radius fractures [3]

Review article Hintringer W, Rosenauer R, Pezzei C, Quadlbauer S, Jurkowitsch J, Keuchel T, et al. · · 2020 · cited 38 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
A wide range of different classifications exist for distal radius fractures (DRF).
Closing excerpt
By applying the following principles, the surgeon may be assisted in choosing the ideal form of treatment approach and implant selection.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (176 words)

A wide range of different classifications exist for distal radius fractures (DRF). Most of them are based on plane X-rays and do not give us any information on how to treat these fractures. A biomechanical understanding of the mechanical forces underlying each fracture type is important to treat each injury specifically and ensure the optimal choice for stabilization. The main cause of DRFs are forces acting on the carpus and the radius as well as the position of the wrist in relation to the radius. Reconstructing the mechanism of the injury gives insight into which structures are involved, such as ruptured ligaments, bone fragments as well as the dislocated osteoligamentous units. This article attempts to define certain key fragments, which seem crucial to reduce and stabilize each type of DRF. Once the definition is established, an ideal implant can be selected to sufficiently maintain reduction of these key fragments. Additionally, the perfect approach is selected. By applying the following principles, the surgeon may be assisted in choosing the ideal form of treatment approach and implant selection.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 32193681 · DOI · PMC7181558

Mapping wrist motion: 3D CT analysis after scapholunate ligament transection [4]

Research article Promny D, Gill D, Lyer S, Alexiou C, Buder T, Neuhuber W, et al. · · 2025 · cited 6 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
The injury of the scapholunate (SL) ligament is common in wrist traumas leading to pain and reduced wrist function.
Closing excerpt
While we observed significant rotational changes for the scaphoid, other carpal bones showed less pronounced alterations, emphasizing the complexity of wrist biomechanics.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (236 words)

The injury of the scapholunate (SL) ligament is common in wrist traumas leading to pain and reduced wrist function. The wrist's unique joint design and possible underlying theories as the carpal row theory were subject to earlier investigations studying wrist kinematics. Nevertheless, a comprehensive understanding of how SL ligament injuries affect wrist biomechanics is still lacking. Through a quantitative analysis of carpal bone motion patterns, we evaluated the impact on wrist kinematics occurring after SL ligament injury. We conducted a study using computer tomography imaging to analyse wrist kinematics after SL ligament transection in 21 fresh-frozen anatomical specimens. The collected data were then transformed into 3D models, employing both standardized global and object coordinate systems. The study encompassed the evaluation of rotation and translation for each individual carpal bone, as well as the ulna, and all metacarpal bones in reference to the radius. The study showed a significant increase in rotation towards palmar (p < 0.01), particularly notable for the scaphoid, following transection of the SL ligament during palmar flexion. Ulnar deviation did not significantly affect rotation or translation, and radial deviation also showed no significant changes in rotation or translation. The study highlights the significance of the SL ligament in wrist kinematics, revealing that SL ligament tears lead to changes in wrist motion. While we observed significant rotational changes for the scaphoid, other carpal bones showed less pronounced alterations, emphasizing the complexity of wrist biomechanics.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 39092658 · DOI · PMC11996708

Key reviews and meta-analyses

The most cited review-type papers among PubMed’s best-match results for this heading, listed with bibliographic details only. Follow the links for the full text and access terms.

  • Research article Foveal TFCC tear classification and treatment [5]
    Atzei A, Luchetti R · Hand Clin · 2011 · cited 175 times (Europe PMC)
  • Research article New trends in arthroscopic management of type 1-B TFCC injuries with DRUJ instability [6]
    Atzei A · J Hand Surg Eur Vol · 2009 · cited 137 times (Europe PMC)
  • Research article Wrist osteoarthritis [7]
    Laulan J, Marteau E, Bacle G · Orthop Traumatol Surg Res · 2015 · cited 90 times (Europe PMC)
  • Research article A revolution in the management of fractures of the distal radius? [8]
    Downing ND, Karantana A · J Bone Joint Surg Br · 2008 · cited 82 times (Europe PMC)
  • Research article Wrist ganglion treatment: systematic review and meta-analysis [9]
    Head L, Gencarelli JR, Allen M, Boyd KU · J Hand Surg Am · 2015 · cited 79 times (Europe PMC)
  • Research article The distal interosseous membrane: current concepts in wrist anatomy and biomechanics [10]
    Moritomo H · J Hand Surg Am · 2012 · cited 72 times (Europe PMC)

References

  1. Klauser AS, Halpern EJ, Strobl S, Abd Ellah MMH, Gruber J, Bellmann-Weiler R, et al.. Gout of hand and wrist: the value of US as compared with DECT. . 2018. PMID 29679210 · DOI · PMC6132720
  2. Oka K, Shiode R, Yoshii Y, Tanaka H, Iwahashi T, Murase T. Artificial intelligence to diagnosis distal radius fracture using biplane plain X-rays. . 2021. PMID 34823550 · DOI · PMC8620959
  3. Hintringer W, Rosenauer R, Pezzei C, Quadlbauer S, Jurkowitsch J, Keuchel T, et al.. Biomechanical considerations on a CT-based treatment-oriented classification in radius fractures. . 2020. PMID 32193681 · DOI · PMC7181558
  4. Promny D, Gill D, Lyer S, Alexiou C, Buder T, Neuhuber W, et al.. Mapping wrist motion: 3D CT analysis after scapholunate ligament transection. . 2025. PMID 39092658 · DOI · PMC11996708
  5. Atzei A, Luchetti R. Foveal TFCC tear classification and treatment. Hand Clin. 2011. PMID 21871349 · DOI
  6. Atzei A. New trends in arthroscopic management of type 1-B TFCC injuries with DRUJ instability. J Hand Surg Eur Vol. 2009. PMID 19620186 · DOI
  7. Laulan J, Marteau E, Bacle G. Wrist osteoarthritis. Orthop Traumatol Surg Res. 2015. PMID 25596986 · DOI
  8. Downing ND, Karantana A. A revolution in the management of fractures of the distal radius?. J Bone Joint Surg Br. 2008. PMID 18827233 · DOI
  9. Head L, Gencarelli JR, Allen M, Boyd KU. Wrist ganglion treatment: systematic review and meta-analysis. J Hand Surg Am. 2015. PMID 25708437 · DOI
  10. Moritomo H. The distal interosseous membrane: current concepts in wrist anatomy and biomechanics. J Hand Surg Am. 2012. PMID 22721462 · DOI

About this article

Sources
NLM Medical Subject Headings (definition, synonyms); NCBI PubMed (counts, identifiers); Europe PMC (open-access abstracts and citation counts).
Verification
Every reference was resolved against PubMed on 2026-10-31; title, year and DOI matched.
Review state
automated source verified; no human expert review has been recorded yet.
Version
1, last updated 2026-10-31.

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At a glance

12,675
PubMed records on this heading
20%
published since 2020
1,400
review articles
269
randomized trials
10
verified references below

Counts come from PubMed on 2026-10-31; they show how much has been written, not how strong the evidence is.

Related topics See all →

  • JointsAnatomy and Physiology
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  • Hip JointAnatomy and Physiology
  • Shoulder JointAnatomy and Physiology
  • Patellofemoral JointAnatomy and Physiology

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