Definition and research guide
This page combines a MeSH definition, publication statistics and selected research abstracts. It is a starting point for reading the literature, not a medical textbook or a systematic evidence review.
Content available: 4 complete abstracts (928 words), 10 references. Full article text is not stored or reproduced here; follow the PMID, DOI or PMC links to read the original sources and their access terms.
Definition
An activity distinguished primarily by an element of risk in trying to obtain a desired goal, e.g., playing a game of chance for money.
Definition: NLM Medical Subject Headings (MeSH) scope note (Public domain (U.S. National Library of Medicine); attribution requested). View the MeSH record.
Also known as: Gamblings; Gambling, Pathological; Gamblings, Pathological; Pathological Gamblings; Pathological Gambling; Gambling, Pathologic.
Where it fits in the MeSH classification
- Broader topics
- Risk-Taking; Disruptive, Impulse Control, and Conduct Disorders
Research landscape
PubMed indexes 8,040 records tagged with the MeSH heading “Gambling” (counts retrieved 2026-10-31). 2,497 of them (31.1%) were published from 2020 onward, and the busiest period so far is 2010-2019 with 3,378 records.
Reviews account for 873 records (10.9%) and meta-analyses for 113. Randomized controlled trials number 327 (4.1%) as a share of all records on the topic.
Show the data
| Period | Records |
|---|---|
| through 1999 | 519 |
| 2000-2009 | 1,646 |
| 2010-2019 | 3,378 |
| 2020 onward | 2,497 |
Publication-type chart data
| Type | Records | Share |
|---|---|---|
| Reviews | 873 | 10.9% |
| Meta-analyses | 113 | 1.4% |
| Randomized controlled trials | 327 | 4.1% |
Method: PubMed query "Gambling"[MeSH Terms] with publication-type and date filters, retrieved 2026-10-31.
Reading the evidence in psychiatry and psychology
Research on mental health and behaviour relies on questionnaires, interviews and rating scales rather than physical measurements, so how a condition was defined and measured shapes every result. Many studies are observational or small, placebo responses can be large, and findings in one group or culture may not carry over to another. Nothing on this page is advice about diagnosis or treatment; anyone worried about their mental health should talk to a qualified clinician. Check how outcomes were measured, who took part and how long they were followed.
Evidence from open-access studies
These open-access studies come from PubMed’s best-match results for this heading (papers whose main topic it is), ranked here by citation count, with one recent addition. Each abstract is reproduced in full under its recorded open licence so that you can read the authors’ own words. They illustrate the literature; they are not a systematic summary of it. Citation counts measure attention, not reliability or clinical benefit.
| Study / authors | Year | Source label / design | Europe PMC citations | Licence / source |
|---|---|---|---|---|
| Gambling disorder comorbidity a narrative review | 2025 | Review article Design not recorded in structured metadata | 22 | cc by PMID 40177908 · DOI · PMC11980244 |
| What is the impact of sports-related gambling advertising on gambling behaviour? A systematic review | 2025 | Systematic review Design not recorded in structured metadata | 16 | cc by PMID 39797658 · DOI · PMC11907332 |
| Research priorities in gambling: Findings of a large-scale expert study | 2025 | Research article Design not recorded in structured metadata | 12 | cc by PMID 41026532 · DOI · PMC12486284 |
| Mindfulness-based interventions for gambling disorder: A systematic review | 2026 | Systematic review Design not recorded in structured metadata | 1 | cc by PMID 41632115 · DOI · PMC13132419 |
Gambling disorder comorbidity a narrative review [1]
Abstract reading summary — source excerpts
- Opening excerpt
- Introduction: Problematic and pathological gambling (PG) lead to major adverse consequences for individuals, their families, and society and is highly comorbid with numerous other mental health disorders.
- Closing excerpt
- Conclusions: Over the past 15 years, significant progress has been made in understanding and treating GD and its psychiatric comorbidities, with evidence highlighting the reciprocal relationships between GD and conditions like substance use, mood and anxiety disorders.
- Interpretation limits
- Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (161 words)
Introduction: Problematic and pathological gambling (PG) lead to major adverse consequences for individuals, their families, and society and is highly comorbid with numerous other mental health disorders.Methods: This narrative review summarized population-based, cross-sectional, treatment and prospective studies on gambling disorder and comorbidity over the past 14 years.Results: These studies show a high rate of comorbidity of PG and substance and alcohol use disorders, mood and anxiety disorders. Prospective studies indicate that, in some cases, gambling precedes the onset of the comorbid disorder, while in other instances, the temporal relationship is reversed. Women face greater psychiatric comorbidity and are more likely to have mood disorders, suicidality, mania, anxiety and alcohol dependence. Treatment of PG can be effective by improving the gambling and depressive symptoms of PG.Conclusions: Over the past 15 years, significant progress has been made in understanding and treating GD and its psychiatric comorbidities, with evidence highlighting the reciprocal relationships between GD and conditions like substance use, mood and anxiety disorders.
Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 40177908 · DOI · PMC11980244
What is the impact of sports-related gambling advertising on gambling behaviour? A systematic review [2]
Abstract reading summary — source excerpts
- Opening excerpt
- Background and aimsGambling is a public health issue and widespread advertising of gambling products may contribute to gambling harms.
- Closing excerpt
- This association may be more pronounced in higher-risk gamblers who are already at increased risk of harm.
- Interpretation limits
- Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (319 words)
Background and aimsGambling is a public health issue and widespread advertising of gambling products may contribute to gambling harms. Sports-related gambling advertising includes advertising around sports games or for sports betting products. This review aimed to provide the most systematic and up-to-date review of the literature on the association between sports-related gambling advertising and gambling behaviour.MethodsA systematic literature search of quantitative studies up to 13 February 2024 was undertaken following PRISMA guidelines. Inclusion criteria were quantitative studies published in the English language exploring the association between sports-related gambling advertising and gambling behaviour. Traditional database searches (Medline, Scopus, PsychInfo, Web of Science, CINAHL and The Cochrane Library) were undertaken alongside citation, author and website searches. Studies were narratively synthesised, and the overall quality of the evidence was assessed using the Mixed Methods Appraisal Tool (MMAT).ResultsTwenty-two studies were included in this review covering traditional, digital, direct, embedded, inducement and aggregate advertising. The majority (n = 16) of research was undertaken in Australia on adult populations. Results suggest that sports-related gambling advertising is associated with increases in perceived, intended and actual frequency of (n = 6 studies) and expenditure on (n = 3) gambling, unplanned or unintended gambling (n = 2), the likelihood of gambling (n = 2), the likelihood of using a sponsor's product (n = 2) and, in some cases, the complexity or riskiness of bets placed (n = 2). Studies suggest that the self-reported effect may be more pronounced in higher-risk gamblers (n = 7). Preliminary evidence suggests that specific inducements which reduce the riskiness or cost of gambling appear to be particularly influential (n = 3). Limitations of the evidence base include the lack of standardised measures and use of observational designs.ConclusionsExposure to sports-related gambling advertising appears to be associated with increased gambling behaviour for a wide range of advertising media. This association may be more pronounced in higher-risk gamblers who are already at increased risk of harm.
Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 39797658 · DOI · PMC11907332
Research priorities in gambling: Findings of a large-scale expert study [3]
Abstract reading summary — source excerpts
- Opening excerpt
- ObjectiveWhile gambling is a growing public health concern, research resources are limited, and no guidance is available to prioritise research.
- Closing excerpt
- The results provide information for researchers and other stakeholders for future projects and funding.
- Interpretation limits
- Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (263 words)
ObjectiveWhile gambling is a growing public health concern, research resources are limited, and no guidance is available to prioritise research. This study aimed to identify priorities for gambling research on a global scale using a systematic, transparent, and democratic methodology to inform researchers and other stakeholders.MethodsLeading gambling researchers were invited to list gambling-related research questions that can contribute to strengthening evidence-based policy, prevention, and effective early intervention and treatment of problem gambling. Suggestions were consolidated into research options and evaluated against six criteria (Answerability, Feasibility, Effectiveness, Impact on equity and an additional two based on the category of research options: Novelty and Relevance for description-type, Potential for burden reduction and Deliverability for intervention-related options). Stakeholders (n = 14) assigned relative weights to each criterion, and options were ranked according to their weighted research priority scores.ResultsWith input from 46.9% of eligible researchers (n = 307) from 35 countries, 1,361 questions were consolidated into 102 options. Evaluations showed strong agreement between experts, and the top 25 priorities were identified. The results highlight the need for further knowledge about the epidemiology, etiology, and consequences of problem gambling. Top-priority topics indicate the importance of focusing on vulnerable and minority groups, youth, significant others, technological innovations, advertisements, the convergence of gaming and gambling, and co-occurring conditions. Evaluating and tailoring existing measures were prioritised more highly than new interventions, and identifying factors underlying treatment seeking, drop-out and relapse was also considered a priority.ConclusionsThis initiative successfully involved the global research community in identifying gambling research priorities. The results provide information for researchers and other stakeholders for future projects and funding.
Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 41026532 · DOI · PMC12486284
Mindfulness-based interventions for gambling disorder: A systematic review [4]
Abstract reading summary — source excerpts
- Opening excerpt
- Background and aimsGambling disorder (GD) presents significant psychological, financial, and social consequences.
- Closing excerpt
- Discussion and conclusionsMBIs show promise as a complementary treatment for gambling disorders, although small sample sizes and methodological limitations suggest a need for more robust research.
- Interpretation limits
- Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (185 words)
Background and aimsGambling disorder (GD) presents significant psychological, financial, and social consequences. Mindfulness-based interventions (MBIs) have emerged as promising adjunctive treatments. However, the evidence base remains heterogeneous. The present systematic review evaluated the current empirical literature on MBIs for GD, focusing on their efficacy, methodological quality, and limitations.MethodsScopus, PubMed, Web of Science, EBSCO, and PsycINFO were searched for English-language studies published between 2012 and April 2025. The final sample comprised 12 studies: five randomized controlled trials, one controlled pilot study, two repeated-measures studies, one mixed-methods study, and three single-group pretest-posttest studies. A narrative synthesis evaluated MBI impacts.ResultsMBIs consistently reduced gambling frequency and cravings while enhancing psychological outcomes. Studies combining mindfulness with cognitive behavioral therapy showed significant declines in problem gambling behavior. Psychological distress and cravings also decreased notably across interventions. The mindfulness components employed varied in focus and application, adding nuance to outcome interpretation. However, it remains unclear to what extent the observed effects can be attributed to mindfulness-specific mechanisms.Discussion and conclusionsMBIs show promise as a complementary treatment for gambling disorders, although small sample sizes and methodological limitations suggest a need for more robust research.
Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 41632115 · DOI · PMC13132419
Key reviews and meta-analyses
The most cited review-type papers among PubMed’s best-match results for this heading, listed with bibliographic details only. Follow the links for the full text and access terms.
- Research article Prevalence of comorbid disorders in problem and pathological gambling: systematic review and meta-analysis of population surveys [5]
- Research article Global prevalence of gaming disorder: A systematic review and meta-analysis [6]
- Research article Problem gambling worldwide: An update and systematic review of empirical research (2000-2015) [7]
- Research article Early risk and protective factors for problem gambling: A systematic review and meta-analysis of longitudinal studies [8]
- Research article Prevalence of psychiatric co-morbidity in treatment-seeking problem gamblers: A systematic review and meta-analysis [9]
- Research article Prevalence of Adolescent Problem Gambling: A Systematic Review of Recent Research [10]
References
- Sharma R, Weinstein A. Gambling disorder comorbidity a narrative review. . 2025. PMID 40177908 · DOI · PMC11980244
- McGrane E, Pryce R, Field M, Gu S, Moore EC, Goyder E. What is the impact of sports-related gambling advertising on gambling behaviour? A systematic review. . 2025. PMID 39797658 · DOI · PMC11907332
- Czakó A, Potenza MN, Hodgins DC, Yu SM, Wu AMS, Jiménez-Murcia S, et al.. Research priorities in gambling: Findings of a large-scale expert study. . 2025. PMID 41026532 · DOI · PMC12486284
- Tannous A, Demetrovics Z, Chhabra B, Logemann A, Czakó A, Griffiths MD, et al.. Mindfulness-based interventions for gambling disorder: A systematic review. . 2026. PMID 41632115 · DOI · PMC13132419
- Lorains FK, Cowlishaw S, Thomas SA. Prevalence of comorbid disorders in problem and pathological gambling: systematic review and meta-analysis of population surveys. Addiction. 2011. PMID 21210880 · DOI
- Stevens MW, Dorstyn D, Delfabbro PH, King DL. Global prevalence of gaming disorder: A systematic review and meta-analysis. Aust N Z J Psychiatry. 2021. PMID 33028074 · DOI
- Calado F, Griffiths MD. Problem gambling worldwide: An update and systematic review of empirical research (2000-2015). J Behav Addict. 2016. PMID 27784180 · DOI · PMC5370365
- Dowling NA, Merkouris SS, Greenwood CJ, Oldenhof E, Toumbourou JW, Youssef GJ. Early risk and protective factors for problem gambling: A systematic review and meta-analysis of longitudinal studies. Clin Psychol Rev. 2017. PMID 27855334 · DOI
- Dowling NA, Cowlishaw S, Jackson AC, Merkouris SS, Francis KL, Christensen DR. Prevalence of psychiatric co-morbidity in treatment-seeking problem gamblers: A systematic review and meta-analysis. Aust N Z J Psychiatry. 2015. PMID 25735959 · DOI · PMC4438101
- Calado F, Alexandre J, Griffiths MD. Prevalence of Adolescent Problem Gambling: A Systematic Review of Recent Research. J Gambl Stud. 2017. PMID 27372832 · DOI · PMC5445143
About this article
- Sources
- NLM Medical Subject Headings (definition, synonyms); NCBI PubMed (counts, identifiers); Europe PMC (open-access abstracts and citation counts).
- Verification
- Every reference was resolved against PubMed on 2026-11-04; title, year and DOI matched.
- Review state
- automated source verified; no human expert review has been recorded yet.
- Version
- 1, last updated 2026-11-04.
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Evidence strength
EvidenceHelix's computed view of the study designs behind this topic: how common meta-analyses, randomized trials and reviews are, how recent the literature is, and a plain-language reading. It describes the design mix of the literature. It is not a quality appraisal of any study, and it is not medical advice.