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Optical Fibers

Diagnostics and Medical Technology · NLM MeSH · updated 2026-11-04 · version 1

Citations verified against PubMedNot yet clinician-reviewed10 referencesApproximately 4 min read

Thin strands of transparent material, usually glass, that are used for transmitting light waves over long distances.

Table of Contents

1. Definition2. Research landscape3. Reading the evidence4. Open-access studies5. Key reviews6. References7. About this article

Definition and research guide

This page combines a MeSH definition, publication statistics and selected research abstracts. It is a starting point for reading the literature, not a medical textbook or a systematic evidence review.

Content available: 4 complete abstracts (738 words), 10 references. Full article text is not stored or reproduced here; follow the PMID, DOI or PMC links to read the original sources and their access terms.

Definition

Thin strands of transparent material, usually glass, that are used for transmitting light waves over long distances.

Definition: NLM Medical Subject Headings (MeSH) scope note (Public domain (U.S. National Library of Medicine); attribution requested). View the MeSH record.

Also known as: Fiber, Optical; Fibers, Optical; Optical Fiber; Fiber Optic Cables; Cable, Fiber Optic; Cables, Fiber Optic; Fiber Optic Cable; Optic Cable, Fiber.

Where it fits in the MeSH classification

Broader topics
Optical Devices
See also
Fiber Optic Technology

Research landscape

PubMed indexes 4,586 records tagged with the MeSH heading “Optical Fibers” (counts retrieved 2026-11-04). 989 of them (21.6%) were published from 2020 onward, and the busiest period so far is 2010-2019 with 1,846 records.

Reviews account for 230 records (5.0%) and meta-analyses for 4. Randomized controlled trials number 34 (0.7%) as a share of all records on the topic. Randomized trials make up only a small share of this literature, so much of what is known comes from laboratory, observational or descriptive work.

PubMed records by publication periodthrough 1999: 687 records; 2000-2009: 1,064 records; 2010-2019: 1,846 records; 2020 onward: 989 records687through 19991,0642000-20091,8462010-20199892020 onward
Records in PubMed indexed with this heading, by publication period. Real counts from NCBI E-utilities; the final period covers only part of the current year. Volume reflects how much has been published, not how strong the evidence is.
Show the data
PeriodRecords
through 1999687
2000-20091,064
2010-20191,846
2020 onward989
Share of records by publication typeReviews: 5.0 percent; Meta-analyses: 0.1 percent; Randomized controlled trials: 0.7 percentReviews5.0% (230)Meta-analyses0.1% (4)Randomized controlled trials0.7% (34)
Share of all PubMed records on this heading that carry each publication type. Types overlap with other records, so the shares do not sum to 100%.
Publication-type chart data
Publication types among 4,586 PubMed records
TypeRecordsShare
Reviews2305.0%
Meta-analyses40.1%
Randomized controlled trials340.7%

Method: PubMed query "Optical Fibers"[MeSH Terms] with publication-type and date filters, retrieved 2026-11-04.

Reading the evidence in diagnostics and medical technology

A test or device is judged by how well it detects a condition, how often it gives false alarms or misses cases, and whether using it improves outcomes for people. Accuracy depends on who is tested and how common the condition is, so a test that performs well in a specialist hospital can perform differently in the community. Check the reference standard, the population studied, the sensitivity and specificity and whether results were confirmed in a separate group.

Evidence from open-access studies

These open-access studies come from PubMed’s best-match results for this heading (papers whose main topic it is), ranked here by citation count, with one recent addition. Each abstract is reproduced in full under its recorded open licence so that you can read the authors’ own words. They illustrate the literature; they are not a systematic summary of it. Citation counts measure attention, not reliability or clinical benefit.

Study comparison — selected abstracts, not a systematic review
Study / authorsYearSource label / designEurope PMC citationsLicence / source
Mn2+-activated dual-wavelength emitting materials toward wearable optical fibre temperature sensor
Song E, Chen M, Chen Z, Zhou Y, Zhou W, Sun HT, et al.
2022Research article
Design not recorded in structured metadata
67cc by
PMID 35443755 · DOI · PMC9021195
Optical Fiber Sensors and Sensing Networks: Overview of the Main Principles and Applications
Pendão C, Silva I
2022Review article
Design not recorded in structured metadata
55cc by
PMID 36236653 · DOI · PMC9570792
Proof of Concept for a Quick and Highly Sensitive On-Site Detection of SARS-CoV-2 by Plasmonic Optical Fibers and Molecularly Imprinted Polymers
Cennamo N, D'Agostino G, Perri C, Arcadio F, Chiaretti G, Parisio EM, et al.
2021Research article
Design not recorded in structured metadata
52cc by
PMID 33804378 · DOI · PMC7957720
Transmission matrix of a multimode fiber: In-line vs off-axis holography
Ivanina A, Lochocki B, Koglbauer A, Sokolov S, Goorden SA, Amitonova LV
2026Research article
Design not recorded in structured metadata
0cc by
PMID 41650213 · DOI · PMC12880716

Mn2+-activated dual-wavelength emitting materials toward wearable optical fibre temperature sensor [1]

Research article Song E, Chen M, Chen Z, Zhou Y, Zhou W, Sun HT, et al. · · 2022 · cited 67 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
Photothermal sensing is crucial for the creation of smart wearable devices.
Closing excerpt
This study also provides a framework for creating transition-metal-activated luminescence materials.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (170 words)

Photothermal sensing is crucial for the creation of smart wearable devices. However, the discovery of luminescent materials with suitable dual-wavelength emissions is a great challenge for the construction of stable wearable optical fibre temperature sensors. Benefiting from the Mn2+-Mn2+ superexchange interactions, a dual-wavelength (530/650 nm)-emitting material Li2ZnSiO4:Mn2+ is presented via simple increasing the Mn2+ concentration, wherein the two emission bands have different temperature-dependent emission behaviours, but exhibit quite similar excitation spectra. Density functional theory calculations, coupled with extended X-ray absorption fine structure and electron-diffraction analyses reveal the origins of the two emission bands in this material. A wearable optical temperature sensor is fabricated by incorporating Li2ZnSiO4:Mn2+ in stretchable elastomer-based optical fibres, which can provide thermal-sensitive emissions at dual- wavelengths for stable ratiometric temperature sensing with good precision and repeatability. More importantly, a wearable mask integrated with this stretchable fibre sensor is demonstrated for the detection of physiological thermal changes, showing great potential for use as a wearable health monitor. This study also provides a framework for creating transition-metal-activated luminescence materials.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 35443755 · DOI · PMC9021195

Optical Fiber Sensors and Sensing Networks: Overview of the Main Principles and Applications [2]

Review article Pendão C, Silva I · · 2022 · cited 55 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
Optical fiber sensors present several advantages in relation to other types of sensors.
Closing excerpt
Moreover, it includes an overview and discussion of a less common architecture, where optical sensing and Wireless Sensor Networks (WSNs) are integrated to harness the benefits of both worlds.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (193 words)

Optical fiber sensors present several advantages in relation to other types of sensors. These advantages are essentially related to the optical fiber properties, i.e., small, lightweight, resistant to high temperatures and pressure, electromagnetically passive, among others. Sensing is achieved by exploring the properties of light to obtain measurements of parameters, such as temperature, strain, or angular velocity. In addition, optical fiber sensors can be used to form an Optical Fiber Sensing Network (OFSN) allowing manufacturers to create versatile monitoring solutions with several applications, e.g., periodic monitoring along extensive distances (kilometers), in extreme or hazardous environments, inside structures and engines, in clothes, and for health monitoring and assistance. Most of the literature available on this subject focuses on a specific field of optical sensing applications and details their principles of operation. This paper presents a more broad overview, providing the reader with a literature review that describes the main principles of optical sensing and highlights the versatility, advantages, and different real-world applications of optical sensing. Moreover, it includes an overview and discussion of a less common architecture, where optical sensing and Wireless Sensor Networks (WSNs) are integrated to harness the benefits of both worlds.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 36236653 · DOI · PMC9570792

Proof of Concept for a Quick and Highly Sensitive On-Site Detection of SARS-CoV-2 by Plasmonic Optical Fibers and Molecularly Imprinted Polymers [3]

Research article Cennamo N, D'Agostino G, Perri C, Arcadio F, Chiaretti G, Parisio EM, et al. · · 2021 · cited 52 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
The rapid spread of the Coronavirus Disease 2019 (COVID-19) pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pathogen has generated a huge international public health emergency.
Closing excerpt
Furthermore, a relatively fast response time (about 10 min) to the virus was obtained without the use of additional reagents.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (253 words)

The rapid spread of the Coronavirus Disease 2019 (COVID-19) pandemic, caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pathogen has generated a huge international public health emergency. Currently the reference diagnostic technique for virus determination is Reverse Transcription Polymerase Chain Reaction (RT-PCR) real time analysis that requires specialized equipment, reagents and facilities and typically 3-4 h to perform. Thus, the realization of simple, low-cost, small-size, rapid and point-of-care diagnostics tests has become a global priority. In response to the current need for quick, highly sensitive and on-site detection of the SARS-CoV-2 virus in several aqueous solutions, a specific molecularly imprinted polymer (MIP) receptor has been designed, realized, and combined with an optical sensor. More specifically, the proof of concept of a SARS-CoV-2 sensor has been demonstrated by exploiting a plasmonic plastic optical fiber sensor coupled with a novel kind of synthetic MIP nano-layer, especially designed for the specific recognition of Subunit 1 of the SARS-CoV-2 Spike protein. First, we have tested the effectiveness of the developed MIP receptor to bind the Subunit 1 of the SARS-CoV-2 spike protein, then the results of preliminary tests on SARS-CoV-2 virions, performed on samples of nasopharyngeal (NP) swabs in universal transport medium (UTM) and physiological solution (0.9% NaCl), were compared with those obtained with RT-PCR. According to these preliminary results, the sensitivity of the proposed optical-chemical sensor proved to be higher than the RT-PCR one. Furthermore, a relatively fast response time (about 10 min) to the virus was obtained without the use of additional reagents.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 33804378 · DOI · PMC7957720

Transmission matrix of a multimode fiber: In-line vs off-axis holography [4]

Research article Ivanina A, Lochocki B, Koglbauer A, Sokolov S, Goorden SA, Amitonova LV · · 2026

Abstract reading summary — source excerpts
Opening excerpt
Multimode fibers (MMFs) hold great promise for a variety of imaging applications.
Closing excerpt
These experimental findings provide a basis for choosing and optimizing holographic techniques in MMF-based imaging setups.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (122 words)

Multimode fibers (MMFs) hold great promise for a variety of imaging applications. However, controlling the complex propagation of light through thousands of modes in MMFs remains a challenging task. To enable precise wavefront control, the MMF transmission matrix (TM) must be accurately measured. In this paper, we compare in-line and off-axis holography as phase retrieval techniques for TM measurement within a single optical setup. The quality of wavefront shaping is analyzed for different target shapes, including single-mode and complex free-form projections. Our findings reveal a trade-off in wavefront shaping: while in-line holography achieves superior focus quality for single-mode targets, off-axis holography excels in projecting complex-shaped targets. These experimental findings provide a basis for choosing and optimizing holographic techniques in MMF-based imaging setups.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 41650213 · DOI · PMC12880716

Key reviews and meta-analyses

The most cited review-type papers among PubMed’s best-match results for this heading, listed with bibliographic details only. Follow the links for the full text and access terms.

  • Research article Optical chemical pH sensors [5]
    Wencel D, Abel T, McDonagh C · Anal Chem · 2014 · cited 222 times (Europe PMC)
  • Research article Fiber-optic chemical sensors and biosensors (2008-2012) [6]
    Wang XD, Wolfbeis OS · Anal Chem · 2013 · cited 164 times (Europe PMC)
  • Research article Towards a Uniform Metrological Assessment of Grating-Based Optical Fiber Sensors: From Refractometers to Biosensors [7]
    Chiavaioli F, Gouveia CAJ, Jorge PAS, Baldini F · Biosensors (Basel) · 2017 · cited 139 times (Europe PMC)
  • Research article High-Q optical sensors for chemical and biological analysis [8]
    Luchansky MS, Bailey RC · Anal Chem · 2012 · cited 119 times (Europe PMC)
  • Research article Fiber Bragg grating sensors toward structural health monitoring in composite materials: challenges and solutions [9]
    Kinet D, Mégret P, Goossen KW, Qiu L, Heider D, Caucheteur C · Sensors (Basel) · 2014 · cited 115 times (Europe PMC)
  • Research article Fiber-Optic Chemical Sensors and Biosensors (2015-2019) [10]
    Wang XD, Wolfbeis OS · Anal Chem · 2020 · cited 113 times (Europe PMC)

References

  1. Song E, Chen M, Chen Z, Zhou Y, Zhou W, Sun HT, et al.. Mn2+-activated dual-wavelength emitting materials toward wearable optical fibre temperature sensor. . 2022. PMID 35443755 · DOI · PMC9021195
  2. Pendão C, Silva I. Optical Fiber Sensors and Sensing Networks: Overview of the Main Principles and Applications. . 2022. PMID 36236653 · DOI · PMC9570792
  3. Cennamo N, D'Agostino G, Perri C, Arcadio F, Chiaretti G, Parisio EM, et al.. Proof of Concept for a Quick and Highly Sensitive On-Site Detection of SARS-CoV-2 by Plasmonic Optical Fibers and Molecularly Imprinted Polymers. . 2021. PMID 33804378 · DOI · PMC7957720
  4. Ivanina A, Lochocki B, Koglbauer A, Sokolov S, Goorden SA, Amitonova LV. Transmission matrix of a multimode fiber: In-line vs off-axis holography. . 2026. PMID 41650213 · DOI · PMC12880716
  5. Wencel D, Abel T, McDonagh C. Optical chemical pH sensors. Anal Chem. 2014. PMID 24180284 · DOI
  6. Wang XD, Wolfbeis OS. Fiber-optic chemical sensors and biosensors (2008-2012). Anal Chem. 2013. PMID 23140530 · DOI
  7. Chiavaioli F, Gouveia CAJ, Jorge PAS, Baldini F. Towards a Uniform Metrological Assessment of Grating-Based Optical Fiber Sensors: From Refractometers to Biosensors. Biosensors (Basel). 2017. PMID 28635665 · DOI · PMC5487959
  8. Luchansky MS, Bailey RC. High-Q optical sensors for chemical and biological analysis. Anal Chem. 2012. PMID 22111937 · DOI · PMC3264793
  9. Kinet D, Mégret P, Goossen KW, Qiu L, Heider D, Caucheteur C. Fiber Bragg grating sensors toward structural health monitoring in composite materials: challenges and solutions. Sensors (Basel). 2014. PMID 24763215 · DOI · PMC4029641
  10. Wang XD, Wolfbeis OS. Fiber-Optic Chemical Sensors and Biosensors (2015-2019). Anal Chem. 2020. PMID 31665884 · DOI

About this article

Sources
NLM Medical Subject Headings (definition, synonyms); NCBI PubMed (counts, identifiers); Europe PMC (open-access abstracts and citation counts).
Verification
Every reference was resolved against PubMed on 2026-11-04; title, year and DOI matched.
Review state
automated source verified; no human expert review has been recorded yet.
Version
1, last updated 2026-11-04.

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At a glance

4,586
PubMed records on this heading
22%
published since 2020
230
review articles
34
randomized trials
10
verified references below

Counts come from PubMed on 2026-11-04; they show how much has been written, not how strong the evidence is.

Related topics See all →

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