Definition and research guide
This page combines a MeSH definition, publication statistics and selected research abstracts. It is a starting point for reading the literature, not a medical textbook or a systematic evidence review.
Content available: 4 complete abstracts (939 words), 10 references. Full article text is not stored or reproduced here; follow the PMID, DOI or PMC links to read the original sources and their access terms.
Definition
Stones in the ureter that are formed in the kidney. They are rarely more than 5 mm in diameter for larger renal stones cannot enter ureters. They are often lodged at the ureteral narrowing and can cause excruciating renal colic.
Definition: NLM Medical Subject Headings (MeSH) scope note (Public domain (U.S. National Library of Medicine); attribution requested). View the MeSH record.
Also known as: Calculi, Ureteral; Calculus, Ureteral; Ureteral Calculus.
Where it fits in the MeSH classification
- Broader topics
- Ureterolithiasis; Urinary Calculi
Related concepts
Research landscape
PubMed indexes 7,745 records tagged with the MeSH heading “Ureteral Calculi” (counts retrieved 2026-11-04). 1,255 of them (16.2%) were published from 2020 onward, and the busiest period so far is through 1999 with 3,591 records.
Reviews account for 599 records (7.7%) and meta-analyses for 151. Randomized controlled trials number 450 (5.8%) as a share of all records on the topic.
Show the data
| Period | Records |
|---|---|
| through 1999 | 3,591 |
| 2000-2009 | 1,238 |
| 2010-2019 | 1,661 |
| 2020 onward | 1,255 |
Publication-type chart data
| Type | Records | Share |
|---|---|---|
| Reviews | 599 | 7.7% |
| Meta-analyses | 151 | 1.9% |
| Randomized controlled trials | 450 | 5.8% |
Method: PubMed query "Ureteral Calculi"[MeSH Terms] with publication-type and date filters, retrieved 2026-11-04.
Reading the evidence in kidney, urology and women's health
Kidney, urinary and reproductive health research uses lab markers (such as creatinine), imaging, symptom scores and registry data on pregnancy and birth. Findings about pregnancy are especially sensitive to who was studied and when in pregnancy exposure occurred. Nothing on this page is advice about treatment, fertility or pregnancy; speak to a qualified clinician. Check the population, the outcome measured and whether the study accounted for other health differences between groups.
Evidence from open-access studies
These open-access studies come from PubMed’s best-match results for this heading (papers whose main topic it is), ranked here by citation count, with one recent addition. Each abstract is reproduced in full under its recorded open licence so that you can read the authors’ own words. They illustrate the literature; they are not a systematic summary of it. Citation counts measure attention, not reliability or clinical benefit.
Contemporary treatment trends for upper urinary tract stones in a total population analysis in Germany from 2006 to 2019: will shock wave lithotripsy become extinct? [1]
Abstract reading summary — source excerpts
- Opening excerpt
- PurposeTo describe the change in upper urinary tract stone management in Germany over a 14-year period.
- Closing excerpt
- These changes may be attributed to enormous technological advances of the endoscopic armamentarium and to reimbursement issues.
- Interpretation limits
- Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (149 words)
PurposeTo describe the change in upper urinary tract stone management in Germany over a 14-year period.MethodsUsing remote data processing we analyzed the nationwide German billing data from 2006 to 2019. To analyze the clinics' case numbers and regional trends, we used the reimbursement.INFO tool based on standardized quality reports of all German hospitals. To also cover shock wave lithotripsy (SWL) as an outpatient procedure, we analyzed the research database of the Institute for Applied Health Research with a representative anonymous sample of 4 million insured persons.ResultsThe number of inpatient interventional therapies for upper tract urolithiasis in Germany increased from 70,099 cases in 2006 to 94,815 cases in 2019 (trend p ConclusionWe observed an increase in interventional therapy for upper tract urolithiasis in Germany with a dramatic shift from SWL to endoscopic/percutaneous treatment. These changes may be attributed to enormous technological advances of the endoscopic armamentarium and to reimbursement issues.
Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 34453580 · DOI · PMC8813696
Differentiation of distal ureteral stones and pelvic phleboliths using a convolutional neural network [2]
Abstract reading summary — source excerpts
- Opening excerpt
- The objectives were to develop and validate a Convolutional Neural Network (CNN) using local features for differentiating distal ureteral stones from pelvic phleboliths, compare the CNN method with a semi-quantitative method and with radiologists' assessments and to evaluate whether the assessment of a calcification and its local surroundings is sufficient for discriminating ureteral stones from pelvic phleboliths in non-contrast-enhanced CT (NECT).
- Closing excerpt
- However, more than local features are needed to reach optimal discrimination.
- Interpretation limits
- Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (257 words)
The objectives were to develop and validate a Convolutional Neural Network (CNN) using local features for differentiating distal ureteral stones from pelvic phleboliths, compare the CNN method with a semi-quantitative method and with radiologists' assessments and to evaluate whether the assessment of a calcification and its local surroundings is sufficient for discriminating ureteral stones from pelvic phleboliths in non-contrast-enhanced CT (NECT). We retrospectively included 341 consecutive patients with acute renal colic and a ureteral stone on NECT showing either a distal ureteral stone, a phlebolith or both. A 2.5-dimensional CNN (2.5D-CNN) model was used, where perpendicular axial, coronal and sagittal images through each calcification were used as input data for the CNN. The CNN was trained on 384 calcifications, and evaluated on an unseen dataset of 50 stones and 50 phleboliths. The CNN was compared to the assessment by seven radiologists who reviewed a local 5 × 5 × 5 cm image stack surrounding each calcification, and to a semi-quantitative method using cut-off values based on the attenuation and volume of the calcifications. The CNN differentiated stones and phleboliths with a sensitivity, specificity and accuracy of 94%, 90% and 92% and an AUC of 0.95. This was similar to a majority vote accuracy of 93% and significantly higher (p = 0.03) than the mean radiologist accuracy of 86%. The semi-quantitative method accuracy was 49%. In conclusion, the CNN differentiated ureteral stones from phleboliths with higher accuracy than the mean of seven radiologists' assessments using local features. However, more than local features are needed to reach optimal discrimination.
Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 32107579 · DOI · PMC7867560
Percutaneous nephrolithotomy versus flexible ureteroscopic lithotripsy in the treatment of upper urinary tract stones: a meta-analysis comparing clinical efficacy and safety [3]
Abstract reading summary — source excerpts
- Opening excerpt
- BackgroundUpper urinary tract stones is the most common diseases in urology.
- Closing excerpt
- 61; P ConclusionsIn the treatment of upper urinary tract stones, the stones clearance rate of PCNL is higher than fURL, and the safety of fURL is higher than PCNL.
- Interpretation limits
- Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (191 words)
BackgroundUpper urinary tract stones is the most common diseases in urology. Percutaneous nephrolithotomy (PCNL) and ureteroscopic lithotripsy (fURL) are common treatment, but both their efficacy and safety are controversial. Thus we aim to evaluate the efficacy and safety of PCNL and fURL in the treatment of upper urinary tract stones, providing a reference for clinical work.MethodsPubMed, Web of Science, Embase and CNKI were searched through Apr. 1, 2019 to identify eligible studies. Data were analyzed by using RevMan 5.3 and Stata 12.0 software. Pooled relative risks (RRs) or weighted mean difference (WMD) with 95% confidence intervals (CIs) were calculated using fixed or random effects methods. Publication bias and sensitivity analysis were performed.ResultsFour randomized controlled trials (RCTs), fifteen cohort studies involving 1822 patients were included. Stone-free rate of PCNL was significantly high than that of fURL (RR: 1.07; 95% CI: 1.03, 1.12; P = 0.0004). The decline of hemoglobin in PCNL was significantly high than that of fURL (WMD: 1.07; 95% CI: 0.54, 1.61; P ConclusionsIn the treatment of upper urinary tract stones, the stones clearance rate of PCNL is higher than fURL, and the safety of fURL is higher than PCNL.
Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 32711510 · DOI · PMC7382049
Pediatric ureteral stenting: state-of-the-art review [4]
Abstract reading summary — source excerpts
- Opening excerpt
- PURPOSE: In this scoping review, we mapped the available clinical evidence on the use of double-J (DJ) ureteral stents in pediatric patients across reconstructive, stone-related, and other endourological indications, synthesizing contemporary data on techniques, sizing, dwell time, removal strategies, outcomes, and emerging technologies.
- Closing excerpt
- Overall, careful patient selection, planned dwell duration, and structured follow-up remain central to optimizing outcomes, while prospective multicenter studies are needed to strengthen the evidence base.
- Interpretation limits
- Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (342 words)
PURPOSE: In this scoping review, we mapped the available clinical evidence on the use of double-J (DJ) ureteral stents in pediatric patients across reconstructive, stone-related, and other endourological indications, synthesizing contemporary data on techniques, sizing, dwell time, removal strategies, outcomes, and emerging technologies. METHODS: A scoping review was conducted in accordance with the PRISMA Extension for Scoping Reviews (PRISMA-ScR). The review protocol was prospectively registered in PROSPERO (CRD420251147003). PubMed, Scopus, Cochrane Library, and Web of Science were searched without date limits to 9 September 2025. Original clinical studies on double-J (DJ) ureteral stents in children were screened, data were extracted into a harmonized database, and risk of bias was appraised using RoB 2, ROBINS-I, or the Joanna Briggs Institute checklist as appropriate. RESULTS: Fifty studies (2003–2025) were included. In reconstruction, internal DJ and externalized stents achieved similar success after pyeloplasty; externalized options commonly enabled office removal without general anesthesia (GA) but often increased length of stay and/or operating time. During ureteroneocystostomy for vesicoureteral reflux, routine stenting was associated with worse adjusted short-term outcomes; these findings are consistent with selective use. In stone disease, routine pre-stenting before ureteroscopy or extracorporeal shock-wave lithotripsy did not improve stone-free rates and increased infectious morbidity; when performed, a short dwell time (~ 2 weeks) was adequate. Across indications, modifiable drivers of morbidity included prolonged dwell, bilateral placement, and multiple lifetime stents. Practical aids included the “Age + 10 cm” length rule and strategies that reduce GA exposure (e.g., stent-on-string with disciplined protocols). Magnetic DJ systems showed high outpatient retrieval success with familiar complication profiles, while anti-biofilm/anti-encrustation coatings remain promising but require pediatric clinical validation. CONCLUSION: Pediatric ureteral stenting practices vary widely across indications. The mapped literature suggests broadly comparable success between internal and externalized stents in reconstruction, while highlighting the importance of dwell time, anesthesia exposure, and individualized decision-making. In stone disease, routine pre-stenting does not appear to confer consistent benefit. Overall, careful patient selection, planned dwell duration, and structured follow-up remain central to optimizing outcomes, while prospective multicenter studies are needed to strengthen the evidence base.
Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 41954662 · DOI · PMC13065543
Key reviews and meta-analyses
The most cited review-type papers among PubMed’s best-match results for this heading, listed with bibliographic details only. Follow the links for the full text and access terms.
- Research article Clinical practice. Acute renal colic from ureteral calculus [5]
- Research article Medical therapy to facilitate the passage of stones: what is the evidence? [6]
- Research article Predictors of Urinary Infections and Urosepsis After Ureteroscopy for Stone Disease: a Systematic Review from EAU Section of Urolithiasis (EULIS) [7]
- Research article Outcomes of stenting after uncomplicated ureteroscopy: systematic review and meta-analysis [8]
- Research article What is the stone-free rate following flexible ureteroscopy for kidney stones? [9]
- Research article A systematic review of medical therapy to facilitate passage of ureteral calculi [10]
References
- Herout R, Baunacke M, Groeben C, Aksoy C, Volkmer B, Schmidt M, et al.. Contemporary treatment trends for upper urinary tract stones in a total population analysis in Germany from 2006 to 2019: will shock wave lithotripsy become extinct?. . 2022. PMID 34453580 · DOI · PMC8813696
- Jendeberg J, Thunberg P, Lidén M. Differentiation of distal ureteral stones and pelvic phleboliths using a convolutional neural network. . 2021. PMID 32107579 · DOI · PMC7867560
- Chen Y, Wen Y, Yu Q, Duan X, Wu W, Zeng G. Percutaneous nephrolithotomy versus flexible ureteroscopic lithotripsy in the treatment of upper urinary tract stones: a meta-analysis comparing clinical efficacy and safety. . 2020. PMID 32711510 · DOI · PMC7382049
- Altunhan A, Soyturk S, Herrmann TRW, Gauhar V, Tokas T, Sultan S, et al.. Pediatric ureteral stenting: state-of-the-art review. . 2026. PMID 41954662 · DOI · PMC13065543
- Teichman JM. Clinical practice. Acute renal colic from ureteral calculus. N Engl J Med. 2004. PMID 14960744 · DOI
- Seitz C, Liatsikos E, Porpiglia F, Tiselius HG, Zwergel U. Medical therapy to facilitate the passage of stones: what is the evidence?. Eur Urol. 2009. PMID 19560860 · DOI
- Chugh S, Pietropaolo A, Montanari E, Sarica K, Somani BK. Predictors of Urinary Infections and Urosepsis After Ureteroscopy for Stone Disease: a Systematic Review from EAU Section of Urolithiasis (EULIS). Curr Urol Rep. 2020. PMID 32211969 · DOI
- Nabi G, Cook J, N'Dow J, McClinton S. Outcomes of stenting after uncomplicated ureteroscopy: systematic review and meta-analysis. BMJ. 2007. PMID 17311851 · DOI · PMC1828345
- Ghani KR, Wolf JS. What is the stone-free rate following flexible ureteroscopy for kidney stones?. Nat Rev Urol. 2015. PMID 25868563 · DOI
- Singh A, Alter HJ, Littlepage A. A systematic review of medical therapy to facilitate passage of ureteral calculi. Ann Emerg Med. 2007. PMID 17681643 · DOI
About this article
- Sources
- NLM Medical Subject Headings (definition, synonyms); NCBI PubMed (counts, identifiers); Europe PMC (open-access abstracts and citation counts).
- Verification
- Every reference was resolved against PubMed on 2026-11-04; title, year and DOI matched.
- Review state
- automated source verified; no human expert review has been recorded yet.
- Version
- 1, last updated 2026-11-04.
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Evidence strength
EvidenceHelix's computed view of the study designs behind this topic: how common meta-analyses, randomized trials and reviews are, how recent the literature is, and a plain-language reading. It describes the design mix of the literature. It is not a quality appraisal of any study, and it is not medical advice.