A psychological intervention by community pharmacies to prevent depression in adults with subthreshold depression and long-term conditions: the CHEMIST pilot RCT · Pilot randomised controlled trial: protocol changes
Pilot randomised controlled trial: protocol changes
CC BY 4.0 · NIHR Journals Library · approximately 1 min read
The current protocol is version 4.2 (dated 14 June 2018).
The general practice database search criteria included refining the search to patient postal codes within 2 miles of the participating CHEMIST CP. Feedback from several general practices suggested that this particular search criteria was complex and time-consuming for practice staff to implement, resulting in some general practices withdrawing their initial involvement in the study. So as not to exclude patients from receiving information about the study owing to the practicalities of conducting searches on general practice systems, this postal code restriction was removed from the search criteria in month 5 of recruitment.
A request to extend the pilot RCT recruitment period by 9 months was submitted to the funder after the study had been recruiting for 9 months (excluding a 3-month delay to the start of recruitment). Both costed and non-costed extension requests were rejected by the funder. Given that recruitment had continued for a longer period of time (14 months) than had been initially planned (8 months), a time-only extension was subsequently approved to allow collection of planned data for all those participants recruited to the pilot RCT (n = 44). The full study was, therefore, extended by 7 months.
Attribution. Elizabeth Littlewood; Carolyn A Chew-Graham; Elizabeth Coleman; Samantha Gascoyne; Claire Sloan; Shehzad Ali et al. (2022). A psychological intervention by community pharmacies to prevent depression in adults with subthreshold depression and long-term conditions: the CHEMIST pilot RCT. NIHR Journals Library. Copyright © Queen’s Printer and Controller of HMSO 2022. This work was produced by Littlewood et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK. Licensed under CC BY 4.0. NCBI Bookshelf NBK579121. CC BY 4.0. Original source ↗. Text reproduced from the Bookshelf XML without changing wording; figures, images and supplements are not reproduced.