Skip to content
EvidenceHelixEvidenceLib · Scientific Encyclopedia
⌘ K

Scientific library

EvidenceLib encyclopediaAll articles A–Z2,835Open textbooks209Open-access articles1,406Cancer study catalog458How it is made

My workspace this browser

Saved pages0Notes & annotations0

Recently viewed

Explore by field

Cancer and Oncology182Genetics and Genomics170Neuroscience185Cardiovascular Medicine180Immunology142Pharmacology173Molecular Biology161Infectious Diseases150Rare and Inherited Diseases181Clinical Research173Anatomy and Physiology613Drugs and Chemicals621Psychiatry and Psychology185Public Health and Nutrition178Diagnostics and Medical Technology125Respiratory Medicine113Digestive System and Liver91Metabolism and Endocrine Disease177Bones, Joints, Muscles and Skin213Kidney, Urology and Women's Health173Eye, Ear, Nose and Throat55
Plans & pricingCompare EvidenceHelix workspace plans
Library›Open textbooks›Development and evaluation of a complex ePrescribing-based Antimicrobial Stewardship (ePAMS+) intervention for hospitals: a mixed method study›References

Continue where you left off ()

Explore more with EvidenceHelix Workspace

Compare studies, analyze evidence and create research reports with premium tools.

Explore Researcher plans

Development and evaluation of a complex ePrescribing-based Antimicrobial Stewardship (ePAMS+) intervention for hospitals: a mixed method study · References

References

CC BY 4.0 · National Institute for Health and Care Research · approximately 4 min read

  1. Mureyi D, Cresswell K, Sivyer K, Heed A, Weir CJ, Adamestam I, et al. The development of a complex digital and behavioural Antimicrobial Stewardship intervention for hospitals in England. BMC Med Inform Decis Mak 2024. 10.21203/rs.3.rs-3715230/v1
  2. Ladenheim D, Cramp E, Patel N. Are current electronic prescribing systems facilitating antimicrobial stewardship in acute National Health Service Hospital Trusts in the East of England? J Hosp Infect 2016;94:200–1. 10.1016/j.jhin.2016.07.01727575656
  3. Madar IK, Coleman JJ, Slee A, Pontefract SK. Do electronic prescribing systems in English hospitals support antimicrobial stewardship? An analysis of ‘Start Smart–Then Focus’ functionality. Clin Ther 2017;39:e4. 10.1016/j.clinthera.2017.05.016
  4. Santillo M, Sivyer K, Krusche A, Mowbray F, Jones N, Peto TE, et al. Intervention planning for Antibiotic Review Kit (ARK): a digital and behavioural intervention to safely review and reduce antibiotic prescriptions in acute and general medicine. J Antimicrob Chemother 2019;74:3362–70. 10.1093/jac/dkz33331430366
  5. Powers EM, Shiffman RN, Melnick ER, Hickner A, Sharifi M. Efficacy and unintended consequences of hard-stop alerts in electronic health record systems: a systematic review. J Am Med Inform Assoc 2018;25:1556–66. 10.1093/jamia/ocy11230239810
  6. Tolley C. An Investigation of Healthcare Professionals’ Experiences of Training and Using Electronic Prescribing Systems: Four Literature Reviews and Two Qualitative Studies Undertaken in the UK Hospital Context [dissertation]. Durham: Durham University; 2018.
  7. McCain CL. The right mix to support electronic medical record training: classroom computer-based training and blended learning. J Nurses Staff Dev 2008;24:151–4. 10.1097/01.NND.0000320673.65824.db18685473
  8. Brown CL, Reygate K, Slee A, Coleman JJ, Pontefract SK, Bates DW, et al. A literature review of the training offered to qualified prescribers to use electronic prescribing systems: why is it so important? Int J Pharm Pract 2017;25:195–202. 10.1111/ijpp.1229627488258
  9. Ruiz JG, Mintzer MJ, Leipzig RM. The impact of e-learning in medical education. Acad Med 2006;81:207–12. 10.1097/00001888-200603000-0000216501260
  10. Coxeter P, Del Mar CB, McGregor L, Beller EM, Hoffmann TC. Interventions to facilitate shared decision making to address antibiotic use for acute respiratory infections in primary care. Cochrane Database Syst Rev 2015;2015:CD010907. 10.1002/14651858.CD010907.pub2
  11. Mowbray F, Sivyer K, Santillo M, Jones N, Peto TE, Walker AS, et al. Patient engagement with antibiotic messaging in secondary care: a qualitative feasibility study of the ‘review and revise’ experience. Pilot Feasibility Stud 2020;6:43. 10.1186/s40814-020-00590-532280483
  12. Butler CC, Kinnersley P, Prout H, Rollnick S, Edwards A, Elwyn G. Antibiotics and shared decision-making in primary care. J Antimicrob Chemother 2001;48:435–40. 10.1093/jac/48.3.43511533013
  13. Meyers DC, Durlak JA, Wandersman A. The quality implementation framework: a synthesis of critical steps in the implementation process. Am J Community Psychol 2012;50:462–80. 10.1007/s10464-012-9522-x22644083
  14. World Health Organization. Global Antimicrobial Resistance and Use Surveillance System (GLASS) Report: 2021. Geneva: World Health Organization; 2021. URL: www.who.int/publications/i/item/9789240036345 (accessed 15 October 2025).
  15. World Health Organization. Global Action Plan on Antimicrobial Resistance. Geneva: World Health Organization; 2015. URL: www.who.int/publications/i/item/9789241509763 (accessed 15 October 2025).
  16. O’Neill J. Antimicrobial Resistance: Tackling a Crisis for the Health and Wealth of Nations. London: Review on Antimicrobial Resistance; 2014. URL: https://amr-review.org/sites/default/files/AMR%20Review%20Paper%20-%20Tackling%20a%20crisis%20for%20the%20health%20and%20wealth%20of%20nations_1.pdf (accessed 15 October 2025).
  17. Goossens H, Ferech M, Vander Stichele R, Elseviers M; ESAC Project Group. Outpatient antibiotic use in Europe and association with resistance: a cross-national database study. Lancet 2005;365:579–87. 10.1016/S0140-6736(05)17907-015708101
  18. Cresswell K, Hinder S, Sheikh A, Pontefract S, Watson NW, Price D, et al. ePrescribing-based antimicrobial stewardship practices in an English National Health Service Hospital: qualitative interview study among medical prescribers and pharmacists. JMIR Form Res 2023;7:e37863. 10.2196/3786337279044
  19. Ashiru-Oredope D, Sharland M, Charani E, McNulty C, Cooke J; ARHAI Antimicrobial Stewardship Group. Improving the quality of antibiotic prescribing in the NHS by developing a new antimicrobial stewardship programme: Start Smart—Then Focus. J Antimicrob Chemother 2012;67:i51–63. 10.1093/jac/dks20222855879
  20. NHS England. Commissioning for Quality and Innovation (CQUIN) Guidance for 2017–2019. London: NHS England; 2018. URL: www.england.nhs.uk/publication/commissioning-for-quality-and-innovation-cquin-guidance-for-2017-2019/ (accessed 15 October 2025).
  21. National Institute for Health and Care Excellence. Antimicrobial Stewardship: Systems and Processes for Effective Antimicrobial Medicine Use. London: NICE; 2015. URL: www.nice.org.uk/guidance/ng15 (accessed 15 October 2025).
  22. Weir CJ, Adamestam I, Sharp R, Ennis H, Heed A, Williams R, et al. A complex ePrescribing-based AntiMicrobial Stewardship (ePAMS+) intervention for hospitals combining technological and behavioural components: protocol for a feasibility trial. Pilot Feasibility Stud 2023;9:18. 10.1186/s40814-022-01230-w36709308
  23. UK Health Security Agency. English Surveillance Programme for Antimicrobial Utilisation and Resistance (ESPAUR): Report 2020 to 2021. London: UKHSA; 2021. URL: www.gov.uk/government/publications/english-surveillance-programme-antimicrobial-utilisation-and-resistance-espaur-report (accessed 15 October 2025).
  24. ESPAUR SSTF Implementation Subgroup. Start Smart – Then Focus: Antimicrobial Stewardship Toolkit for English Hospitals. London: Public Health England; 2015. URL: www.gov.uk/government/publications/antimicrobial-stewardship-start-smart-then-focus/start-smart-then-focus-antimicrobial-stewardship-toolkit-for-inpatient-care-settings (accessed 15 October 2025).
  25. Copas AJ, Dwan KM, Kirkham JJ, Williamson PR. A model-based correction for outcome reporting bias in meta-analysis. Biostatistics 2014;15:370–83. 10.1093/biostatistics/kxt04624215031
  26. Girling AJ, Hemming K. Statistical efficiency and optimal design for stepped cluster randomized trials. Stat Med 2016;15:2149–66. 10.1002/sim.6850
  27. Wang J, Dong M, Lu Y, Zhao X, Li X, Wen A. Impact of pharmacist interventions on rational prophylactic antibiotic use and cost saving in elective cesarean section. Int J Clin Pharmacol Ther 2015;53:605–15. 10.5414/CP20233426104036
  28. van Daalen FV, Opmeer BC, Prins JM, Geerlings SE, Hulscher M. The economic evaluation of an antibiotic checklist as antimicrobial stewardship intervention. J Antimicrob Chemother 2017;72:3213–21. 10.1093/jac/dkx25928981722
  29. Okumura LM, Riveros BS, Gomes-da-Silva MM, Veroneze I. A cost-effectiveness analysis of two different antimicrobial stewardship programs. Braz J Infect Dis 2016;20:255–61. 10.1016/j.bjid.2016.02.00527094234
  30. Slayton RB, Scott RD, Baggs J, Lessa FC, McDonald LC, Jernigan JA. The cost-benefit of federal investment in preventing Clostridium difficile infections through the use of a multifaceted infection control and antimicrobial stewardship program. Infect Control Hosp Epidemiol 2015;36:681–7. 10.1017/ice.2015.4325783204
  31. Zhou X, Gong J, Su D, Wu Z, Jia X, Wang Y, et al. Effect of pharmacist intervention on antibiotic prophylaxis in orthopedic internal fixation: a retrospective study. Res Social Adm Pharm 2023;19:301–7. 10.1016/j.sapharm.2022.10.00236266174
  32. Gebretekle GB, Mariam DH, Mac S, Abebe W, Alemayehu T, Degu WA, et al. Cost-utility analysis of antimicrobial stewardship programme at a tertiary teaching hospital in Ethiopia. BMJ Open 2021;11:e047515. 10.1136/bmjopen-2020-047515
  33. UK Government. Antimicrobial Resistance (AMR). 2025. URL: www.gov.uk/government/collections/antimicrobial-resistance-amr-information-and-resources (accessed 25 September 2025).
← SynopsisAdditional information →

Attribution. Aziz Sheikh; Jamie Coleman; Antony Chuter; Jillian Beggs; Richard Lilford; Ann Slee et al. (2026). Development and evaluation of a complex ePrescribing-based Antimicrobial Stewardship (ePAMS+) intervention for hospitals: a mixed method study. National Institute for Health and Care Research. Copyright © 2026 Sheikh et al. Licensed under CC BY 4.0. NCBI Bookshelf NBK623660. CC BY 4.0. Original source ↗. Text reproduced from the Bookshelf XML without changing wording; figures, images and supplements are not reproduced.

In this chapter Contents

  • References

Source

OpenStax source file ↗

Source record ↗

EvidenceLib is a research-education resource, not medical advice. It does not diagnose, prescribe or recommend starting, stopping or changing any treatment. Talk to a qualified clinician about your own situation. Methods, sources and licences · Rights and removal requests · Legal · Support