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Library›Open textbooks›Exercise programme to improve quality of life for patients with end-stage kidney disease receiving haemodialysis: the PEDAL RCT›References

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Exercise programme to improve quality of life for patients with end-stage kidney disease receiving haemodialysis: the PEDAL RCT · References

References

CC BY 4.0 · NIHR Journals Library · approximately 8 min read

  1. Greenwood SA, Koufaki P, Macdonald JH, Bhandari S, Burton JO, Dasgupta I, et al. Randomized Trial - PrEscription of intraDialytic exercise to improve quAlity of Life (PEDAL) in patients receiving hemodialysis. Kidney Int Rep 2021; in press. 10.1016/j.ekir.2021.05.034
  2. Ashby D, Borman N, Burton JO, Corbett R, Davenport A, Farrington K, et al. Renal Association Clinical Practice Guideline on Haemodialysis. BMC Nephrol 2019;20:379. 10.1186/s12882-019-1527-331623578
  3. Stack AG, Molony DA, Rives T, Tyson J, Murthy BV. Association of physical activity with mortality in the US dialysis population. Am J Kidney Dis 2005;45:690–701. 10.1053/j.ajkd.2004.12.01315806472
  4. Sietsema KE, Amato A, Adler SG, Brass EP. Exercise capacity as a predictor of survival among ambulatory patients with end-stage renal disease. Kidney Int 2004;65:719–24. 10.1111/j.1523-1755.2004.00411.x14717947
  5. Knight EL, Ofsthun N, Teng M, Lazarus JM, Curhan GC. The association between mental health, physical function, and hemodialysis mortality. Kidney Int 2003;63:1843–51. 10.1046/j.1523-1755.2003.00931.x12675862
  6. Lowrie EG, Curtin RB, LePain N, Schatell D. Medical outcomes study short form-36: a consistent and powerful predictor of morbidity and mortality in dialysis patients. Am J Kidney Dis 2003;41:1286–92. 10.1016/S0272-6386(03)00361-512776282
  7. Painter P, Carlson L, Carey S, Paul SM, Myll J. Physical functioning and health-related quality-of-life changes with exercise training in hemodialysis patients. Am J Kidney Dis 2000;35:482–92. 10.1016/S0272-6386(00)70202-210692275
  8. DeOreo PB. Hemodialysis patient-assessed functional health status predicts continued survival, hospitalization, and dialysis-attendance compliance. Am J Kidney Dis 1997;30:204–12. 10.1016/S0272-6386(97)90053-69261030
  9. Heiwe S, Jacobson SH. Exercise training for adults with chronic kidney disease. Cochrane Database Syst Rev 2011;10:CD003236. 10.1002/14651858.CD003236.pub2
  10. Heiwe S, Jacobson SH. Exercise training in adults with CKD: a systematic review and meta-analysis. Am J Kidney Dis 2014;64:383–93. 10.1053/j.ajkd.2014.03.02024913219
  11. Cheema BS, Chan D, Fahey P, Atlantis E. Effect of progressive resistance training on measures of skeletal muscle hypertrophy, muscular strength and health-related quality of life in patients with chronic kidney disease: a systematic review and meta-analysis. Sports Med 2014;44:1125–38. 10.1007/s40279-014-0176-824696049
  12. Segura-Ortí E. [Exercise in hemodialysis patients: a literature systematic review.] Nefrologia 2010;30:236–46.20098466
  13. Smart N, Steele M. Exercise training in haemodialysis patients: a systematic review and meta-analysis. Nephrology (Carlton) 2011;16:626–32. 10.1111/j.1440-1797.2011.01471.x21557787
  14. Salhab N, Karavetian M, Kooman J, Fiaccadori E, El Khoury CF. Effects of intradialytic aerobic exercise on hemodialysis patients: a systematic review and meta-analysis. J Nephrol 2019;32:549–66. 10.1007/s40620-018-00565-z30659520
  15. Sheng K, Zhang P, Chen L, Cheng J, Wu C, Chen J. Intradialytic exercise in hemodialysis patients: a systematic review and meta-analysis. Am J Nephrol 2014;40:478–90. 10.1159/00036872225504020
  16. Chung YC, Yeh ML, Liu YM. Effects of intradialytic exercise on the physical function, depression and quality of life for haemodialysis patients: a systematic review and meta-analysis of randomised controlled trials. J Clin Nurs 2017;26:1801–13. 10.1111/jocn.1351427532211
  17. Pu J, Jiang Z, Wu W, Li L, Zhang L, Li Y, et al. Efficacy and safety of intradialytic exercise in haemodialysis patients: a systematic review and meta-analysis. BMJ Open 2019;9:e020633. 10.1136/bmjopen-2017-020633
  18. Young HML, March DS, Graham-Brown MPM, Jones AW, Curtis F, Grantham CS, et al. Effects of intradialytic cycling exercise on exercise capacity, quality of life, physical function and cardiovascular measures in adult haemodialysis patients: a systematic review and meta-analysis. Nephrol Dial Transplant 2018;33:1436–45. 10.1093/ndt/gfy04529608708
  19. Huang M, Lv A, Wang J, Xu N, Ma G, Zhai Z, et al. Exercise training and outcomes in hemodialysis patients: systematic review and meta-analysis. Am J Nephrol 2019;50:240–54. 10.1159/00050244731454822
  20. Zhao QG, Zhang HR, Wen X, Wang Y, Chen XM, Chen N, et al. Exercise interventions on patients with end-stage renal disease: a systematic review. Clin Rehabil 2019;33:147–56. 10.1177/026921551881708330789077
  21. Clarkson MJ, Bennett PN, Fraser SF, Warmington SA. Exercise interventions for improving objective physical function in patients with end-stage kidney disease on dialysis: a systematic review and meta-analysis. Am J Physiol Renal Physiol 2019;316:F856–F872. 10.1152/ajprenal.00317.201830759022
  22. Gomes Neto M, de Lacerda FFR, Lopes AA, Martinez BP, Saquetto MB. Intradialytic exercise training modalities on physical functioning and health-related quality of life in patients undergoing maintenance hemodialysis: systematic review and meta-analysis. Clin Rehabil 2018;32:1189–202. 10.1177/026921551876038029480025
  23. NIHR INVOLVE. NIHR INVOLVE. 2021. URL: www.invo.org.uk/about-involve/ (accessed 13 April 2021).
  24. Department of Health, Social Services and Public Safety, Scottish Government, Welsh Government, Department of Health and Social Care. Start Active, Stay Active: A Report on Physical Activity for Health from the Four Home Countries’ Chief Medical Officers. 2011. URL: http://dh.gov.uk/en/Publicationsandstatistics/Publications/PublicationsPolicyAndGuidance/DH_128209 (accessed 1 December 2019).
  25. Colberg SR, Albright AL, Blissmer BJ, Braun B, Chasan-Taber L, Fernhall B, et al. Exercise and type 2 diabetes: American College of Sports Medicine and the American Diabetes Association: joint position statement. Med Sci Sports Exerc 2010;42:2282–303. 10.1249/MSS.0b013e3181eeb61c21084931
  26. Fleg JL, Forman DE, Berra K, Bittner V, Blumenthal JA, Chen MA, et al. Secondary prevention of atherosclerotic cardiovascular disease in older adults: a scientific statement from the American Heart Association. Circulation 2013;128:2422–46. 10.1161/01.cir.0000436752.99896.2224166575
  27. Segura-Ortí E, Martínez-Olmos FJ. Test-retest reliability and minimal detectable change scores for sit-to-stand-to-sit tests, the six-minute walk test, the one-leg heel-rise test, and handgrip strength in people undergoing hemodialysis. Phys Ther 2011;91:1244–52. 10.2522/ptj.2010014121719637
  28. Abe Y, Matsunaga A, Matsuzawa R, Kutsuna T, Yamamoto S, Yoneki K, et al. Determinants of slow walking speed in ambulatory patients undergoing maintenance hemodialysis. PLOS ONE 2016;11:e0151037. 10.1371/journal.pone.015103727018891
  29. Laurent S, Cockcroft J, Van Bortel L, Boutouyrie P, Giannattasio C, Hayoz D, et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J 2006;27:2588–605. 10.1093/eurheartj/ehl25417000623
  30. Hickson SS, Butlin M, Broad J, Avolio AP, Wilkinson IB, McEniery CM. Validity and repeatability of the Vicorder apparatus: a comparison with the SphygmoCor device. Hypertens Res 2009;32:1079–85. 10.1038/hr.2009.15419779487
  31. Lee PH, Macfarlane DJ, Lam TH, Stewart SM. Validity of the International Physical Activity Questionnaire Short Form (IPAQ-SF): a systematic review. Int J Behav Nutr Phys Act 2011;8:115. 10.1186/1479-5868-8-11522018588
  32. Coutinho-Myrrha MA, Dias RC, Fernandes AA, Araújo CG, Hlatky MA, Pereira DG, Britto RR. Duke Activity Status Index for cardiovascular diseases: validation of the Portuguese translation. Arq Bras Cardiol 2014;102:383–90. 10.5935/abc.2014003124652056
  33. Tinetti ME, Richman D, Powell L. Falls efficacy as a measure of fear of falling. J Gerontol 1990;45:P239–43. 10.1093/geronj/45.6.P2392229948
  34. Gonzalez AM, Filho GJ, Pestana JO, Linhares MM, Silva MH, Moura RM, et al. Effects of Eurocollins solution as aortic flush for the procurement of human pancreas. Transplantation 2005;80:1269–74. 10.1097/01.TP.0000177640.53848.3D16314795
  35. Grbich C. Qualitative Research – An Introduction. London: SAGE Publications Ltd; 1999.
  36. Snape D, Spencer L. The Foundations of Qualitative Research. In Ritchie J, Lewis J, editors. Qualitative Research Practice: A Guide for Social Science Students and Researchers. London: SAGE Publications Ltd; 2003.
  37. Krueger RA, Casey MA. Focus Groups: A Practical Guide for Applied Research. 3rd edn. London: SAGE Publications Ltd; 2000.
  38. Ritchie J, Spencer L. Qualitative Data Analysis for Applied Policy Research. In Bryman A, Burgess RG, editors. Analysing Qualitative Data. New York, NY: Routledge; 1994.
  39. Young HM, Hudson N, Clarke AL, Dungey M, Feehally J, Burton JO, Smith AC. Patient and staff perceptions of intradialytic exercise before and after implementation: a qualitative study. PLOS ONE 2015;10:e0128995. 10.1371/journal.pone.012899526068875
  40. Thompson S, Tonelli M, Klarenbach S, Molzahn A. A qualitative study to explore patient and staff perceptions of intradialytic exercise. Clin J Am Soc Nephrol 2016;11:1024–33. 10.2215/CJN.1198111527026522
  41. Heiwe S, Tollin H. Patients’ perspectives on the implementation of intra-dialytic cycling – a phenomenographic study. Implement Sci 2012;7:68. 10.1186/1748-5908-7-6822831388
  42. Michie S, van Stralen MM, West R. The behaviour change wheel: a new method for characterising and designing behaviour change interventions. Implement Sci 2011;6:42. 10.1186/1748-5908-6-4221513547
  43. Byrne C CF, Castledine C, Davenport A, Dawnay A, Fraser S, Maxwell H, Medcalf JF, Wilkie M, Williams AJ. UK Renal Registry 20th Annual Report of the Renal Association. Nephron 2018;139:1–12. 10.1159/000490958
  44. Macdougall IC, White C, Anker SD, Bhandari S, Farrington K, Kalra PA, et al. Randomized trial comparing proactive, high-dose versus reactive, low-dose intravenous iron supplementation in hemodialysis (PIVOTAL): study design and baseline data. Am J Nephrol 2018;48:260–8. 10.1159/00049355130304714
  45. Saran R, Robinson B, Abbott KC, Agodoa LYC, Bragg-Gresham J, Balkrishnan R, et al. US Renal Data System 2018 Annual Data Report: Epidemiology of Kidney Disease in the United States. Am J Kidney Dis 2019;73:A7–8. 10.1053/j.ajkd.2019.01.00130798791
  46. Goodkin DA, Bragg-Gresham JL, Koenig KG, Wolfe RA, Akiba T, Andreucci VE, et al. Association of comorbid conditions and mortality in hemodialysis patients in Europe, Japan, and the United States: the Dialysis Outcomes and Practice Patterns Study (DOPPS). J Am Soc Nephrol 2003;14:3270–7. 10.1097/01.ASN.0000100127.54107.5714638926
  47. Duranton F, Kramer A, Szwarc I, Bieber B, Gayrard N, Jover B, et al. Geographical variations in blood pressure level and seasonality in hemodialysis patients. Hypertension 2018;71:289–96. 10.1161/HYPERTENSIONAHA.117.1027429255071
  48. Lopes AA, Bragg-Gresham JL, Satayathum S, McCullough K, Pifer T, Goodkin DA, et al. Health-related quality of life and associated outcomes among hemodialysis patients of different ethnicities in the United States: the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am J Kidney Dis 2003;41:605–15. 10.1053/ajkd.2003.5012212612984
  49. Hays RD, Kallich JD, Mapes DL, Coons SJ, Carter WB. Development of the kidney disease quality of life (KDQOL) instrument. Qual Life Res 1994;3:329–38. 10.1007/BF004517257841967
  50. Dimeo F, Wencke M, Krist L, Westhoff T, Rothermund L. Effects of a stamina training programme over 8 weeks in patients after kidney transplantation. Deutsche Zeitschrift fur Sportmedizin 2007;58:204.
  51. Matsumoto Y, Furuta A, Furuta S, Miyajima M, Sugino T, Nagata K, et al. The impact of pre-dialytic endurance training on nutritional status and quality of life in stable hemodialysis patients (Sawada study). Ren Fail 2007;29:587–93. 10.1080/0886022070139215717654322
  52. Jong K, LS. J, Hyun Y, Suk P, Young J, Eun A. Effects of Walking Exercise for Health Status in Patients on Continuous Ambulatory Peritoneal Dialysis. Proceedings of the 41st Congress European Renal Association European Dialysis and Transplantation Association, 15–18 May 2004, Lisbon, Portugal. p. 188.
  53. Afsar B, Siriopol D, Aslan G, Eren OC, Dagel T, Kilic U, et al. The impact of exercise on physical function, cardiovascular outcomes and quality of life in chronic kidney disease patients: a systematic review. Int Urol Nephrol 2018;50:885–904.29344881
  54. Pei G, Tang Y, Tan L, Tan J, Ge L, Qin W. Aerobic exercise in adults with chronic kidney disease (CKD): a meta-analysis. Int Urol Nephrol 2019;51:1787–95.31332699
  55. Barcellos FC, Santos IS, Umpierre D, Bohlke M, Hallal PC. Effects of exercise in the whole spectrum of chronic kidney disease: a systematic review. Clin Kidney J 2015;8:753–65. 10.1093/ckj/sfv09926613036
  56. Matsuzawa R, Hoshi K, Yoneki K, Harada M, Watanabe T, Shimoda T, et al. Exercise training in elderly people undergoing hemodialysis: a systematic review and meta-analysis. Kidney Int Rep 2017;2:1096–110. 10.1016/j.ekir.2017.06.00829270518
  57. Ouzouni S, Kouidi E, Sioulis A, Grekas D, Deligiannis A. Effects of intradialytic exercise training on health-related quality of life indices in haemodialysis patients. Clin Rehabil 2009;23:53–63. 10.1177/026921550809676019114437
  58. Baboolal K, McEwan P, Sondhi S, Spiewanowski P, Wechowski J, Wilson K. The cost of renal dialysis in a UK setting--a multicentre study. Nephrol Dial Transplant 2008;23:1982–9. 10.1093/ndt/gfm87018174268
  59. Painter P, Carlson L, Carey S, Paul SM, Myll J. Low-functioning hemodialysis patients improve with exercise training. Am J Kidney Dis 2000;36:600–8. 10.1053/ajkd.2000.1620010977793
← Discussion and conclusionsAcknowledgements →

Attribution. Sharlene A Greenwood; Pelagia Koufaki; Jamie H Macdonald; Catherine Bulley; Sunil Bhandari; James O Burton et al. (2021). Exercise programme to improve quality of life for patients with end-stage kidney disease receiving haemodialysis: the PEDAL RCT. NIHR Journals Library. Copyright © 2021 Greenwood et al. This work was produced by Greenwood et al. under the terms of a commissioning contract issued by the Secretary of State for Health and Social Care. This is an Open Access publication distributed under the terms of the Creative Commons Attribution CC BY 4.0 licence, which permits unrestricted use, distribution, reproduction and adaption in any medium and for any purpose provided that it is properly attributed. See: https://creativecommons.org/licenses/by/4.0/. For attribution the title, original author(s), the publication source – NIHR Journals Library, and the DOI of the publication must be cited. Licensed under CC BY 4.0. NCBI Bookshelf NBK571307. CC BY 4.0. Original source ↗. Text reproduced from the Bookshelf XML without changing wording; figures, images and supplements are not reproduced.

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