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Perioperative oxygen therapy in patients undergoing surgical procedures: an overview of systematic reviews and meta-analyses · Additional information

Additional information

CC BY 4.0 · National Institute for Health and Care Research · approximately 4 min read

Contributions of authors

Adel Elfeky (https://orcid.org/0000-0001-6579-0929) (Research Fellow, Evidence Synthesis) led the overview, maintained day-to-day running of the project, was involved in all stages of the review process, and drafted and revised the report.

Yen-Fu Chen (https://orcid.org/0000-0002-9446-2761) (Associate Professor, Evidence Synthesis) was involved in the design of the overview, oversaw its conduct and helped draft and revise the report.

Amy Grove (https://orcid.org/0000-0002-8027-7274) (Professor of Health Technology Assessment and Implementation Science and NIHR Advanced Fellow) was involved in the design of the overview, oversaw its conduct and helped draft and revise the report.

Keith Couper (https://orcid.org/0000-0003-2123-2022) (Associate Professor in Emergency and Critical Care) was involved in the design of the overview, oversaw its conduct, provided clinical guidance throughout and helped draft and revise the report.

Rachel Court (https://orcid.org/0000-0002-4567-2586) (Senior Information Specialist) led the database search, designed and ran the searches for the systematic overview, helped manage the references and referencing and contributed to the writing of the final report.

Sara Tomassini (https://orcid.org/0000-0003-2506-3019) (NIHR Academic Clinical Fellow in Anaesthetics) contributed to the title/abstract screening, full-text screening, data extraction, mapping of studies, quality assessment and writing of the final report.

Anna Wilson (https://orcid.org/0000-0003-1351-2227) (Clinical Research Fellow) contributed to the title/abstract screening, full-text screening, data extraction and mapping of studies.

Amy Hooper (https://orcid.org/0009-0007-1159-7198) (Clinical Fellow in Paediatric Emergency Medicine) contributed to the title/abstract screening, full-text screening, data extraction and mapping of studies.

Alexandra Buckle (https://orcid.org/0000-0002-7160-662X) (Academic Foundation Doctor) contributed to data extraction and mapping of studies.

Sharvari Vadeyar (https://orcid.org/0000-0001-9244-8328) (Academic Foundation Doctor in Anaesthesia and Critical Care) contributed to data extraction and mapping of studies.

Marion Thompson (https://orcid.org/0000-0002-6180-231X) (Patient and Public Involvement Representative) helped reviewing mapping of studies, synthesis strategy and interpretation of evidence.

Olalekan Uthman (https://orcid.org/0000-0002-8567-3081) (Professor in Evidence Synthesis) was involved in the design of the overview and helped revise the report.

Joyce Yeung (https://orcid.org/0000-0003-2950-4758) (Associate Clinical Professor) was the principal investigator and the grant holder. She was involved in the design of the overview, oversaw its conduct, provided clinical guidance throughout and helped drafting and revising the report. She also oversaw the public and patient engagement sessions.

Acknowledgements

We thank members of the advisory panel for their inputs and guidance during various stages of the project. We are grateful to Dr Daniel Gallacher for his statistical advice on meta-analyses and meta-regression.

Nitin Arora, Consultant in Anaesthesia and Critical Care, University Hospitals Birmingham NHS Foundation Trust.

Ceri Battle, Critical Care and Emergency Medicine Physiotherapist, Swansea Bay University Health Board.

Ben Creagh-Brown, Consultant Physician in Critical Care, Royal Surrey County Hospital.

Sarah Markham, Patient and Public Involvement member.

Samiran Ray, Paediatric Intensive Care Consultant, Great Ormond Street Hospital for Children NHS Foundation Trust.

Jayne Turner, Critical Care Outreach Lead Nurse, University Hospitals Birmingham NHS Foundation Trust.

Marion Thompson, Patient and Public Involvement member.

Jess Wickins, Surgical Advanced Clinical Practitioner, University Hospitals Birmingham NHS Foundation Trust.

Jane Whitehurst, Patient and Public Involvement member.

Data-sharing statement

Requests for access to data should be addressed to the corresponding author.

Ethics statement

This project was an evidence synthesis of publicly accessible data and therefore did not require ethical approval.

Information governance statement

No personally identifiable information was collected or handled for this evidence synthesis project.

Disclosure of interests

Full disclosure of interests: Completed ICMJE forms for all authors, including all related interests, are available in the toolkit on the NIHR Journals Library report publication page at https://doi.org/10.3310/TNTC4360.

Primary conflicts of interest: Amy Grove, Yen-Fu Chen and Rachel Court are supported by the NIHR Evidence Synthesis Programme (14/25/05). Amy Grove and Rachel Court are supported by NIHR Advanced Fellowship NIHR NIHR300060. Amy Grove is also supported by the NIHR Applied Research Collaboration West Midlands NIHR200165. Sara Tomassini is supported by NIHR Academic Clinical Fellowship ACF-2021-08-003. Yen-Fu Chen is a member of the NIHR Evidence Synthesis Programme Prioritisation and Advisory Group. Amy Grove is a member of the Member of the NIHR HTA Commissioning Committee and a member of the NIHR DSE Fellowship Funding Committee. Keith Couper is a member of NIHR HTA hospital-based prioritisation committee and NIHR RfPB West Midlands funding committee. Joyce Yeung is a member of NIHR HTA General Committee.

Publications

Elfeky A, Chen YF, Grove A, Hooper A, Wilson A, Couper K, et al. Perioperative oxygen therapy: a protocol for an overview of systematic reviews and meta-analyses. Syst Rev 2022;11(1):140. https://doi.org/10.1186/s13643-022-02005-3

Elfeky A, Chen Y-F, Grove A, Couper K, Court R, Tomassini S, et al. Perioperative oxygen therapy: an overview of systematic reviews and meta-analyses [published online ahead of print 6 June 2025]. Br J Anaesth 2025. https://doi.org/10.1016/j.bja.2025.04.020

Disclaimers

This article presents independent research funded by the National Institute for Health and Care Research (NIHR). The views and opinions expressed by authors in this publication are those of the authors and do not necessarily reflect those of the NHS, the NIHR, the HTA programme or the Department of Health and Social Care. If there are verbatim quotations included in this publication the views and opinions expressed by the interviewees are those of the interviewees and do not necessarily reflect those of the authors, those of the NHS, the NIHR, the HTA programme or the Department of Health and Social Care.

← References

Attribution. Adel Elfeky; Yen-Fu Chen; Amy Grove; Keith Couper; Rachel Court; Sara Tomassini et al. (2025). Perioperative oxygen therapy in patients undergoing surgical procedures: an overview of systematic reviews and meta-analyses. National Institute for Health and Care Research. Copyright © 2025 Elfeky et al. Licensed under CC BY 4.0. NCBI Bookshelf NBK618082. CC BY 4.0. Original source ↗. Text reproduced from the Bookshelf XML without changing wording; figures, images and supplements are not reproduced.

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