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Condoms

Diagnostics and Medical Technology · NLM MeSH · updated 2026-11-04 · version 1

Citations verified against PubMedNot yet clinician-reviewed10 referencesApproximately 6 min read

A sheath that is worn over the penis during sexual behavior in order to prevent pregnancy or spread of sexually transmitted disease.

Table of Contents

1. Definition2. Research landscape3. Reading the evidence4. Open-access studies5. Key reviews6. References7. About this article

Definition and research guide

This page combines a MeSH definition, publication statistics and selected research abstracts. It is a starting point for reading the literature, not a medical textbook or a systematic evidence review.

Content available: 4 complete abstracts (1,166 words), 10 references. Full article text is not stored or reproduced here; follow the PMID, DOI or PMC links to read the original sources and their access terms.

Definition

A sheath that is worn over the penis during sexual behavior in order to prevent pregnancy or spread of sexually transmitted disease.

Definition: NLM Medical Subject Headings (MeSH) scope note (Public domain (U.S. National Library of Medicine); attribution requested). View the MeSH record.

Also known as: Condom; Condom Manufacture; Manufacture, Condom.

Where it fits in the MeSH classification

Broader topics
Contraceptive Devices, Male

Research landscape

PubMed indexes 11,623 records tagged with the MeSH heading “Condoms” (counts retrieved 2026-11-04). 1,331 of them (11.5%) were published from 2020 onward, and the busiest period so far is 2010-2019 with 4,553 records.

Reviews account for 687 records (5.9%) and meta-analyses for 114. Randomized controlled trials number 675 (5.8%) as a share of all records on the topic.

PubMed records by publication periodthrough 1999: 2,367 records; 2000-2009: 3,372 records; 2010-2019: 4,553 records; 2020 onward: 1,331 records2,367through 19993,3722000-20094,5532010-20191,3312020 onward
Records in PubMed indexed with this heading, by publication period. Real counts from NCBI E-utilities; the final period covers only part of the current year. Volume reflects how much has been published, not how strong the evidence is.
Show the data
PeriodRecords
through 19992,367
2000-20093,372
2010-20194,553
2020 onward1,331
Share of records by publication typeReviews: 5.9 percent; Meta-analyses: 1.0 percent; Randomized controlled trials: 5.8 percentReviews5.9% (687)Meta-analyses1.0% (114)Randomized controlled trials5.8% (675)
Share of all PubMed records on this heading that carry each publication type. Types overlap with other records, so the shares do not sum to 100%.
Publication-type chart data
Publication types among 11,623 PubMed records
TypeRecordsShare
Reviews6875.9%
Meta-analyses1141.0%
Randomized controlled trials6755.8%

Method: PubMed query "Condoms"[MeSH Terms] with publication-type and date filters, retrieved 2026-11-04.

Reading the evidence in diagnostics and medical technology

A test or device is judged by how well it detects a condition, how often it gives false alarms or misses cases, and whether using it improves outcomes for people. Accuracy depends on who is tested and how common the condition is, so a test that performs well in a specialist hospital can perform differently in the community. Check the reference standard, the population studied, the sensitivity and specificity and whether results were confirmed in a separate group.

Evidence from open-access studies

These open-access studies come from PubMed’s best-match results for this heading (papers whose main topic it is), ranked here by citation count, with one recent addition. Each abstract is reproduced in full under its recorded open licence so that you can read the authors’ own words. They illustrate the literature; they are not a systematic summary of it. Citation counts measure attention, not reliability or clinical benefit.

Study comparison — selected abstracts, not a systematic review
Study / authorsYearSource label / designEurope PMC citationsLicence / source
Effects of a Mobile Health Intervention to Promote HIV Self-testing with MSM in China: A Randomized Controlled Trial
Zhu X, Zhang W, Operario D, Zhao Y, Shi A, Zhang Z, et al.
2019Randomized controlled trial
Design not recorded in structured metadata
70cc by
PMID 30852728 · DOI · PMC6733671
Beliefs and misconceptions about contraception and condom use among adolescents in south-east Nigeria
Mbachu CO, Agu IC, Obayi C, Eze I, Ezumah N, Onwujekwe O
2021Research article
Design not recorded in structured metadata
35cc by
PMID 33407642 · DOI · PMC7789795
Assessment of risky sexual behavior and practice among Aksum University students, Shire Campus, Shire Town, Tigray, Ethiopia, 2017
Kebede A, Molla B, Gerensea H
2018Research article
Design not recorded in structured metadata
35cc by
PMID 29386042 · DOI · PMC5793377
Age-related associations between heavy drinking and inconsistent condom use among unmarried adults: results from the Brazilian National Health Survey
Gomes NL, Lopes CS
2025Research article
Design not recorded in structured metadata
1cc by
PMID 40802357 · DOI · PMC12334172

Effects of a Mobile Health Intervention to Promote HIV Self-testing with MSM in China: A Randomized Controlled Trial [1]

Randomized controlled trial Zhu X, Zhang W, Operario D, Zhao Y, Shi A, Zhang Z, et al. · · 2019 · cited 70 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
This study tested a mobile health (mHealth) intervention program entitled WeTest, delivered via the WeChat mobile app, to promote oral HIV self-testing (HIVST) among MSM in Hefei, China.
Closing excerpt
Findings from this study provide evidence for the feasibility, acceptability and preliminary effects of this mHealth approach to promoting oral HIVST among MSM in China.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (249 words)

This study tested a mobile health (mHealth) intervention program entitled WeTest, delivered via the WeChat mobile app, to promote oral HIV self-testing (HIVST) among MSM in Hefei, China. A total of 100 MSM participants enrolled, completed baseline assessment, were randomly assigned to intervention or control, and completed 6-month follow-up surveys. Intervention participants (n = 50) received two oral HIVST kits and access to WeTest, a private WeChat group which provided app-based messages and referrals to health services related to HIV. Control participants (n = 50) received two oral HIVST kits only. All participants received instructions to upload photographic results of their oral HIVST, which were sent to the project counselor via a secure WeChat online portal; immediate contact and referrals were made to any participants who tested HIV-positive. In GEE analyses adjusting for time effects and baseline confounders, intervention participants had significantly higher rates of HIV testing (adjusted rate ratio RR = 1.99, 95% confidence interval (CI) 1.07-3.84) and, in particular, higher rates of testing via oral HIVST (adjusted RR = 2.17, 95% CI 1.08-4.37) compared with the control group. Significant time effects were also found such that all participants, regardless of group allocation, had significantly higher rates of reporting consistent condom use with main partners (adjusted RR = 18.13, 95% CI 5.19-63.31) and with non-main partners (adjusted RR = 5.33, 95% CI 2.35-12.08). Findings from this study provide evidence for the feasibility, acceptability and preliminary effects of this mHealth approach to promoting oral HIVST among MSM in China.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 30852728 · DOI · PMC6733671

Beliefs and misconceptions about contraception and condom use among adolescents in south-east Nigeria [2]

Research article Mbachu CO, Agu IC, Obayi C, Eze I, Ezumah N, Onwujekwe O · · 2021 · cited 35 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
BackgroundMisconceptions about the usefulness of condoms and other contraceptives still expose many unmarried adolescents to the risk of unwanted teenage pregnancies and sexually-transmitted infections (STIs).
Closing excerpt
Concerted efforts should be made to debunk these wrong beliefs and properly educate adolescents on safe sex practices.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (568 words)

BackgroundMisconceptions about the usefulness of condoms and other contraceptives still expose many unmarried adolescents to the risk of unwanted teenage pregnancies and sexually-transmitted infections (STIs). This study explored beliefs and misconceptions about condoms and other contraceptives among adolescents in Ebonyi state, south-east Nigeria.MethodA qualitative study was undertaken in six local government areas in Ebonyi state, southeast Nigeria. Data were collected within a period of one month from in and out-of-school adolescents aged 13-18 years using twelve focus group discussions (FGD). The data were analyzed using the thematic framework approach.ResultMajority of the adolescents were knowledgeable about methods of contraception, how they are used and their modes of action. They were also knowledgeable about the dual effects of condoms in prevention of pregnancy and STIs. However, some misconceptions that were expressed by some adolescents were that pregnancy could be prevented by the use of (i) hard drugs, (ii) laxatives, (iii) white chlorine, and (iv) boiled alcoholic beverages. Condoms were described by some adolescent boys as reusable. Condoms were also perceived by some adolescents to reduce sexual pleasure, and this opinion was mostly held by boys. Coitus interruptus (withdrawal method) was therefore considered more preferable than condoms for prevention of pregnancy.ConclusionAlthough majority adolescents have knowledge about contraception and condom use, some misconceptions still persist. These misconceptions put many adolescents at increased risk for pregnancy and STIs which are detrimental to their health and wellbeing. Concerted efforts should be made through educational and behaviour change interventions in schools and within communities to debunk persisting misconceptions about contraception including the use of condom, and properly educate adolescents on safe sex practices. Adolescents engage in unprotected sexual intercourse and other risky sexual behaviours because of some mistaken beliefs and wrong impressions about how to prevent unwanted pregnancy. These risky sexual behaviours predispose adolescents to sexually transmitted infections, unsafe abortion and other reproductive health problems. In this qualitative study, we explored some of these mistaken beliefs about condoms and other methods of preventing pregnancy. During focus group discussions, adolescents identified modern contraceptive methods, and described their modes of action and how they are used. They also discussed their contraceptive preferences and perceived effects of condoms on sexual pleasure. Although some of these adolescents were able to correctly mention various types of contraceptives and their modes of action, there were numerous wrong impressions. Hard drugs, laxatives, white chlorine and boiled alcoholic beverage were listed as emergency contraceptive methods. Emergency pills were perceived to work by flushing away spermatozoa from a girl's system after sexual intercourse. Male condoms were perceived to be potentially dangerous because they could break and enter into the body of the female sexual partner. Some adolescent boys had the notion that particular brands of male condoms could be washed and reused. Notions about condom use and sexual pleasure varied for girls and boys. Some adolescent girls perceived that condom use during sex increases sexual pleasure because of the assurance of being protected from STIs and pregnancy. Adolescent boys were of the opinion that condoms interfere with the pleasure of direct 'flesh to flesh' contact during sex. There was a general belief that contraceptive use in early age reduces fertility prospects for boys and girls. Mistaken beliefs about methods of preventing pregnancy persist among adolescents, and this raises concerns about the quality of information they receive. Concerted efforts should be made to debunk these wrong beliefs and properly educate adolescents on safe sex practices.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 33407642 · DOI · PMC7789795

Assessment of risky sexual behavior and practice among Aksum University students, Shire Campus, Shire Town, Tigray, Ethiopia, 2017 [3]

Research article Kebede A, Molla B, Gerensea H · · 2018 · cited 35 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
ObjectiveHaving sex at early age, having multiple sexual partners, having sex while under the influence of alcohol or drugs and unprotected sexual behaviors are the common characteristics of risky sexual behavior which increases risk of individuals to sexuality and reproductive health problems.
Closing excerpt
Unless appropriate age and institutional targeted interventions exist, certain behaviors can place the university students at greater risk of HIV infection and sexually transmitted disease.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (189 words)

ObjectiveHaving sex at early age, having multiple sexual partners, having sex while under the influence of alcohol or drugs and unprotected sexual behaviors are the common characteristics of risky sexual behavior which increases risk of individuals to sexuality and reproductive health problems. Risky sexual behavior is the most common problem in adolescents and young adults which may expose individuals for permanent social, economical, psychological and physical problem. So that this study focus on assessment of risk sexual behavior using institution based cross-sectional study design on 287 randomly selected subjects among Aksum University students.ResultsAlmost 60% students reported to have ever had sexual activity. Of which 86 (83.5%) and 112 (64.4%) reported having inconsistent condom use and multiple sexual partners respectively. Even though more than half of first sexual intercourse (61.5%) starts due to their desire but still peer pressure and alcohol have significant effect. Similarly the study indicated that a significant segment of students have risk sexual behaviors which increase individuals' risk of acquiring HIV/AIDS. Unless appropriate age and institutional targeted interventions exist, certain behaviors can place the university students at greater risk of HIV infection and sexually transmitted disease.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 29386042 · DOI · PMC5793377

Age-related associations between heavy drinking and inconsistent condom use among unmarried adults: results from the Brazilian National Health Survey [4]

Research article Gomes NL, Lopes CS · · 2025 · cited 1 times (Europe PMC)

Abstract reading summary — source excerpts
Opening excerpt
Risky sexual behaviors, such as the nonuse of condoms, are identified in the literature as a possible outcome of excessive alcohol use.
Closing excerpt
However, significant differences were not found for this association between the phases of adulthood.
Interpretation limits
Verbatim excerpts from the authors’ abstract; the closing excerpt may describe a finding, limitation or recommendation. Design, population, effect size and uncertainty have not been independently extracted or appraised. Read the complete abstract and linked paper before interpreting the findings.
Read complete abstract (160 words)

Risky sexual behaviors, such as the nonuse of condoms, are identified in the literature as a possible outcome of excessive alcohol use. However, studies on this topic are focused on the high-risk population, namely young adults, men who have sex with men, and sex workers, which limits the analysis of life stages in this association. Thus, this study aimed to verify, for the first time, the association between heavy drinking, at global-level, and inconsistent condom use among unmarried, not cohabiting Brazilians aged 18 to 59 years in various phases of adulthood. Data were obtained from the 2019 Brazilian National Health Survey (N = 15,835). Adjusted prevalence ratios and confidence intervals were estimated using Poisson regression models stratified by sex. Heavy drinkers, unmarried, not cohabiting adults were significantly more likely to report inconsistent condom use when compared with non-heavy drinkers for all age groups and both sexes. However, significant differences were not found for this association between the phases of adulthood.

Abstract reproduced from the open-access article under the recorded cc by licence; © the authors. PMID 40802357 · DOI · PMC12334172

Key reviews and meta-analyses

The most cited review-type papers among PubMed’s best-match results for this heading, listed with bibliographic details only. Follow the links for the full text and access terms.

  • Research article Theories of reasoned action and planned behavior as models of condom use: a meta-analysis [5]
    Albarracín D, Johnson BT, Fishbein M, Muellerleile PA · Psychol Bull · 2001 · cited 632 times (Europe PMC)
  • Research article Structural approaches to HIV prevention [6]
    Gupta GR, Parkhurst JO, Ogden JA, Aggleton P, Mahal A · Lancet · 2008 · cited 510 times (Europe PMC)
  • Research article Psychosocial correlates of heterosexual condom use: a meta-analysis [7]
    Sheeran P, Abraham C, Orbell S · Psychol Bull · 1999 · cited 433 times (Europe PMC)
  • Research article Global perspectives on the sexual and reproductive health of adolescents: patterns, prevention, and potential [8]
    Bearinger LH, Sieving RE, Ferguson J, Sharma V · Lancet · 2007 · cited 401 times (Europe PMC)
  • Research article Effectiveness of condoms in preventing sexually transmitted infections [9]
    Holmes KK, Levine R, Weaver M · Bull World Health Organ · 2004 · cited 338 times (Europe PMC)
  • Research article Condom effectiveness in reducing heterosexual HIV transmission [10]
    Weller S, Davis K · Cochrane Database Syst Rev · 2002 · cited 310 times (Europe PMC)

References

  1. Zhu X, Zhang W, Operario D, Zhao Y, Shi A, Zhang Z, et al.. Effects of a Mobile Health Intervention to Promote HIV Self-testing with MSM in China: A Randomized Controlled Trial. . 2019. PMID 30852728 · DOI · PMC6733671
  2. Mbachu CO, Agu IC, Obayi C, Eze I, Ezumah N, Onwujekwe O. Beliefs and misconceptions about contraception and condom use among adolescents in south-east Nigeria. . 2021. PMID 33407642 · DOI · PMC7789795
  3. Kebede A, Molla B, Gerensea H. Assessment of risky sexual behavior and practice among Aksum University students, Shire Campus, Shire Town, Tigray, Ethiopia, 2017. . 2018. PMID 29386042 · DOI · PMC5793377
  4. Gomes NL, Lopes CS. Age-related associations between heavy drinking and inconsistent condom use among unmarried adults: results from the Brazilian National Health Survey. . 2025. PMID 40802357 · DOI · PMC12334172
  5. Albarracín D, Johnson BT, Fishbein M, Muellerleile PA. Theories of reasoned action and planned behavior as models of condom use: a meta-analysis. Psychol Bull. 2001. PMID 11271752 · DOI · PMC4780418
  6. Gupta GR, Parkhurst JO, Ogden JA, Aggleton P, Mahal A. Structural approaches to HIV prevention. Lancet. 2008. PMID 18687460 · DOI
  7. Sheeran P, Abraham C, Orbell S. Psychosocial correlates of heterosexual condom use: a meta-analysis. Psychol Bull. 1999. PMID 9990846 · DOI
  8. Bearinger LH, Sieving RE, Ferguson J, Sharma V. Global perspectives on the sexual and reproductive health of adolescents: patterns, prevention, and potential. Lancet. 2007. PMID 17416266 · DOI
  9. Holmes KK, Levine R, Weaver M. Effectiveness of condoms in preventing sexually transmitted infections. Bull World Health Organ. 2004. PMID 15356939 · PMC2622864
  10. Weller S, Davis K. Condom effectiveness in reducing heterosexual HIV transmission. Cochrane Database Syst Rev. 2002. PMID 11869658 · DOI · PMC8407100

About this article

Sources
NLM Medical Subject Headings (definition, synonyms); NCBI PubMed (counts, identifiers); Europe PMC (open-access abstracts and citation counts).
Verification
Every reference was resolved against PubMed on 2026-11-04; title, year and DOI matched.
Review state
automated source verified; no human expert review has been recorded yet.
Version
1, last updated 2026-11-04.

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At a glance

11,623
PubMed records on this heading
11%
published since 2020
687
review articles
675
randomized trials
10
verified references below

Counts come from PubMed on 2026-11-04; they show how much has been written, not how strong the evidence is.

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