Cancer family · grouped by EvidenceHelix from study titles

Brain and nervous system: 38 studies

Public cancer genomics studies in this group, with the collection each belongs to. Open a study for its description, citation and original source links.

• Anaplastic Oligodendroglioma and Anaplastic Oligoastrocytoma (MSK, Neuro Oncol 2017)

  IMPACT sequencing of 22 Anaplastic Oligodendroglioma and Anaplastic Oligoastrocytomas.

  Brain and nervous systemMSK studiesSource code difgPubMed 1

• Brain Lower Grade Glioma (TCGA, Firehose Legacy)

  TCGA Brain Lower Grade Glioma. Source data from GDAC Firehose (http://gdac.broadinstitute.org/runs/stddata__2016_01_28/data/LGG/20160128/). Previously known as TCGA Provisional.

  Brain and nervous systemTCGA Firehose LegacySource code difg

• Brain Lower Grade Glioma (TCGA, PanCancer Atlas)

  Brain Lower Grade Glioma TCGA PanCancer data. The original data is here (https://gdc.cancer.gov/about-data/publications/pancanatlas). The publications are here (https://www.cell.com/pb-assets/consortium/pancanceratlas…

  Brain and nervous systemTCGA PanCancer AtlasSource code difgPubMed 12

• Brain Tumor PDXs (Mayo Clinic, Clin Cancer Res 2020)

  WES on a total of 106 PDXs and 80 PDXs have the matched germline (blood) samples sequenced. A total of 66 PDXs have RNASeq available

  Brain and nervous systemOther published and consortium studiesSource code difgPubMed 1

• Cutaneous Neurofibroma Data Resource (CTF, Scientific Data 2021)

  The data are contributed by researchers funded by the Children's Tumor Foundation. The reprocessing of the raw data is managed by the NF Open Science Initiative NF Open Science Initiative .

  Brain and nervous systemOther published and consortium studiesSource code nfibPubMed 2

• Diffuse Glioma (GLASS Consortium)

  Whole genome or whole exome sequencing analysis of temporally separated diffuse glioma tumor/normal pairs from 329 adult patients. The data provided is based on the May 31, 2022 version and can be accessed at Synapse…

  Brain and nervous systemOther published and consortium studiesSource code difgPubMed 2

• Diffuse Glioma (GLASS Consortium, Nature 2019)

  Whole genome or whole exome sequencing analysis of temporally separated diffuse glioma tumor/normal pairs from 222 adult patients.

  Brain and nervous systemOther published and consortium studiesSource code difgPubMed 1

• Glioblastoma (Columbia, Nat Med. 2019)

  Whole-exome sequencing of 32 out of 42 glioblastomas patients with matched normals.

  Brain and nervous systemOther published and consortium studiesSource code difgPubMed 1

• Glioblastoma (CPTAC, Cell 2021)

  Proteogenomic and metabolomic characterization of human glioblastoma. Whole genome or whole exome sequencing of 99 samples. Generated by CPTAC.

  Brain and nervous systemOther published and consortium studiesSource code difgPubMed 1

• Glioblastoma (Randomized Clinical Trial, Nat Med. 2019) - iAtlas Harmonized

  Whole-exome sequencing and neoantigen landscape analysis of 30 recurrent glioblastomas and their matched normals from a randomized, multi-institution clinical trial to evaluate immune responses and survival following…

  Brain and nervous systemOther published and consortium studiesSource code difgPubMed 1

• Glioblastoma (TCGA, Cell 2013)

  Whole-exome and/or whole-genome sequencing of 291 of the 577 glioblastoma tumor/normal pairs. The Cancer Genome Atlas (TCGA) Glioblastoma Project.

  Brain and nervous systemTCGA (other releases)Source code difgPubMed 1

• Glioblastoma (TCGA, Nature 2008)

  Targeted sequencing in 91 of the 206 primary glioblastoma tumors (143 with matched normals) from the Cancer Genome Atlas (TCGA) Glioblastoma Project.

  Brain and nervous systemTCGA (other releases)Source code difgPubMed 1

• Glioblastoma Multiforme (TCGA, Firehose Legacy)

  TCGA Glioblastoma Multiforme. Source data from GDAC Firehose (http://gdac.broadinstitute.org/runs/stddata__2016_01_28/data/GBM/20160128/). Previously known as TCGA Provisional.

  Brain and nervous systemTCGA Firehose LegacySource code difg

• Glioblastoma Multiforme (TCGA, PanCancer Atlas)

  Glioblastoma Multiforme TCGA PanCancer data. The original data is here (https://gdc.cancer.gov/about-data/publications/pancanatlas). The publications are here (https://www.cell.com/pb-assets/consortium/pancanceratlas/…

  Brain and nervous systemTCGA PanCancer AtlasSource code difgPubMed 12

• Glioma (MSK, Clin Cancer Res 2019)

  Targeted sequencing on MSK-IMPACT and FMI Panels of 1004 samples (837 with matched normals) from 923 glioma patients.

  Brain and nervous systemMSK studiesSource code difgPubMed 1

• Glioma (MSK, Nature 2019)

  Targeted Sequencing of CSF samples (91 samples with 86 matched normals) from 42 glioma patients.

  Brain and nervous systemMSK studiesSource code difgPubMed 1

• Hereditary SDHB-Mutant Pheochromocytomas and Paragangliomas (A5 Consortium, Nature Comm 2025)

  Whole genome sequencing of 94 Hereditary SDHB-mutant pheochromocytomas (PC) and paragangliomas (PG) tumors and their matched normals.

  Brain and nervous systemOther published and consortium studiesSource code hnscPubMed 1

• IDH-mutated Diffuse Glioma (MSK, Clin Cancer Res 2024)

  Targeted sequencing of 73 IDH-mutated low-grade gliomas and their matched normal pairs via MSK-IMPACT. The data is available on Synapse (https://www.synapse.org/#!Synapse:syn52658621/wiki/624065).

  Brain and nervous systemMSK studiesSource code difgPubMed 1

• Low-Grade Gliomas (UCSF, Science 2014)

  Whole exome sequencing of 23 grade II glioma tumor/normal pairs.

  Brain and nervous systemOther published and consortium studiesSource code difgPubMed 1

• Malignant Peripheral Nerve Sheath Tumor (MSK, Nat Genet 2014)

  Whole exome sequencing of 15 malignant peripheral nerve sheath tumor/normal pairs.

  Brain and nervous systemMSK studiesSource code mpnstPubMed 1

• Medulloblastoma (Broad, Nature 2012)

  Whole exome sequencing of 92 primary medulloblastoma tumor/normal pairs.

  Brain and nervous systemOther published and consortium studiesSource code mblPubMed 1

• Medulloblastoma (DKFZ, Nature 2017)

  Whole genome or whole exome sequencing of 491 previously untreated Medulloblastoma tumor/normal pairs.

  Brain and nervous systemOther published and consortium studiesSource code mblPubMed 1

• Medulloblastoma (ICGC, Nature 2012)

  Comprehensive profiling of 125 matched tumor and germline medulloblastoma samples

  Brain and nervous systemOther published and consortium studiesSource code mblPubMed 1

• Medulloblastoma (PCGP, Nature 2012)

  Whole genome sequencing of 37 medulloblastoma tumors and their matched normals from the Pediatric Cancer Genome Project (PCGP), a joint project by St. Jude Children's Research Hospital and Washington University.

  Brain and nervous systemOther published and consortium studiesSource code mblPubMed 1

• Medulloblastoma (Sickkids, Nature 2016)

  Whole-genome sequencing of 46 recurrent medulloblastoma samples.

  Brain and nervous systemOther published and consortium studiesSource code mblPubMed 1

• Nerve Sheath Tumors (Johns Hopkins, 2024)

  Whole-exome sequencing of 134 nerve sheath tumor samples with their matched normals. The raw data is contributed by Johns Hopkins University researchers funded by the Neurofibromatosis Therapeutic Acceleration Program…

  Brain and nervous systemOther published and consortium studiesSource code nstPubMed 1

• Neuroblastoma (AMC Amsterdam, Nature 2012)

  Whole genome sequencing of 87 primary neuroblastoma tumors and their matched normals.

  Brain and nervous systemOther published and consortium studiesSource code nblPubMed 1

• Neuroblastoma (Broad, Nat Genet 2013)

  Whole Genome and Whole Exome sequencing of 240 high-risk neuroblastoma tumor/normal pairs.

  Brain and nervous systemOther published and consortium studiesSource code nblPubMed 1

• Neuroblastoma (Broad, Nature 2015)

  Whole-genome sequencing of 56 neuroblastoma tumor/normal pairs.

  Brain and nervous systemOther published and consortium studiesSource code nblPubMed 1

• Pediatric Brain Cancer (CPTAC/CHOP, Cell 2020)

  Integrated proteogenomic characterization across major histological types of pediatric brain cancer . We report a comprehensive proteogenomics analysis, including whole-genome sequencing, RNA sequencing, and proteomic…

  Brain and nervous systemOther published and consortium studiesSource code brainPubMed 1

• Pediatric Low-Grade Glioma (CTF, Acta Neuropathol 2021)

  Whole genome sequencing of pediatric low-grade gliomas with neurofibromatosis. The data are contributed by researchers funded by the Children's Tumor Foundation (CTF). The reprocessing of the raw data is managed by NF…

  Brain and nervous systemOther published and consortium studiesSource code lggnosPubMed 1

• Pediatric Neuroblastoma (TARGET, 2018)

  Whole genome or whole exome sequencing on 1089 NBL samples. Comprehensive profiling of 1089 NBL samples. TARGET data is intended exclusively for biomedical research using pediatric data (i.e., the research objectives…

  Brain and nervous systemNCI TARGETSource code nbl

• Pheochromocytoma and Paraganglioma (TCGA, Cell 2017)

  Whole exome sequencing of 178 Pheochromocytoma or Paraganglioma tumor/normal pairs.

  Brain and nervous systemTCGA (other releases)Source code soft_tissuePubMed 1

• Pheochromocytoma and Paraganglioma (TCGA, Firehose Legacy)

  TCGA Pheochromocytoma and Paraganglioma. Source data from GDAC Firehose (http://gdac.broadinstitute.org/runs/stddata__2016_01_28/data/PCPG/20160128/). Previously known as TCGA Provisional.

  Brain and nervous systemTCGA Firehose LegacySource code mnet

• Pheochromocytoma and Paraganglioma (TCGA, PanCancer Atlas)

  Pheochromocytoma and Paraganglioma TCGA PanCancer data. The original data is here (https://gdc.cancer.gov/about-data/publications/pancanatlas). The publications are here (https://www.cell.com/pb-assets/consortium/panc…

  Brain and nervous systemTCGA PanCancer AtlasSource code soft_tissuePubMed 12

• Pilocytic Astrocytoma (ICGC, Nature Genetics 2013)

  Whole-genome sequencing of 96 pilocytic astrocytoma tumor/normal pairs. Conducted by the International Cancer Genome Consortium (ICGC) PedBrain Tumor Project.

  Brain and nervous systemOther published and consortium studiesSource code pastPubMed 1

• Primary CNS Lymphoma (MSK, Clin Cancer Res 2024)

  Targeted sequencing of 86 samples from 44 patients with primary CNS lymphoma with their matched normals via HemePACT. A Phase II study assessing Long-Term Response to Ibrutinib Monotherapy in recurrent or refractory C…

  Brain and nervous systemMSK studiesSource code pcnslPubMed 1

• Schwannoma (Children's Tumor Foundation, Acta Neuropathologica 2020)

  Whole exome sequencing of 30 patients with schwannomatosis-associated schwannomas, along with their matched normal samples. These data originate from the Synodos for Schwannomatosis project and were contributed by res…

  Brain and nervous systemOther published and consortium studiesSource code schwPubMed 1